{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:37:45Z","timestamp":1777894665456,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["World j. otorhinolaryngol.-head neck surg."],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Thyroid carcinoma (TC) accounts for almost 0.5%\u20131% of total malignancies. Its incidence is increasing rapidly worldwide. Several studies have drawn up the epidemiological profile of TC and its clinical and pathological features. However, to date, no similar studies have been conducted in Tunisia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our institute.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We collected a sample of 192 cases of TC. It consisted of 31 males and 161 females (83.8%) with a sex\u2010ratio M\/F of 0.19. The mean age was 46.4 years. Papillary thyroid carcinoma was the most frequent histological subtype. The multifocality rate was 33.8%. The mean size of TC was 2.2\u2009\u00b1\u20091.9\u2009cm. 60.9% of TC were staged pT1 and 20.3% had nodal involvement. Papillary thyroid microcarcinomas were noted in 37.5% of cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results were consistent with those of the literature. A high proportion of pT1 and pN0 tumors were noted in our series, suggesting that TC's diagnosis and management was performed at an early stage of the disease in our institution. In addition, our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our institution. Further studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.<\/jats:p><\/jats:sec>","DOI":"10.1002\/wjo2.147","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T12:33:12Z","timestamp":1703680392000},"page":"37-42","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8599-0888","authenticated-orcid":false,"given":"Maissa","family":"Ben Thayer","sequence":"first","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Khanchel","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imen","family":"Helal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorra","family":"Chiboub","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck surgery Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedhli","family":"Raoueh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ehsen","family":"Ben Brahim","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja","family":"Jouini","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aschraf","family":"Chadli\u2010Debbiche","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis Tunis El Manar University  Tunis Tunisia"},{"name":"Depatment of Pathology Habib Thameur's Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Cancer Statistics Review 1975\u20102014\u2010SEER Statistics [Internet].SEER. 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