{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T19:13:30Z","timestamp":1718133210623},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["World j. otorhinolaryngol.-head neck surg."],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>With the spread of the epidemic worldwide, an increasing number of doctors abroad have observed the following atypical symptoms of coronavirus disease 2019 (COVID\u201019): olfactory or taste disorders. Therefore, clarifying the incidence and clinical characteristics of olfactory and taste disorders in Chinese COVID\u201019 patients is of great significance and urgency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A retrospective study was conducted, which included 229 severe acute respiratory syndrome\u00a0coronavirus 2 confirmed patients, through face\u2010to\u2010face interviews and telephone follow\u2010up. Following the completion of questionnaires, the patients participating in the study, were categorized according to the degree of olfactory and taste disorders experienced, and the proportion of each clinical type of patient with olfactory and taste disorders and the time when symptoms appeared were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 229 patients, 31 (13.54%) had olfactory dysfunction, and 44 (19.21%) had gustatory dysfunction. For the patients with olfactory dysfunction, 6 (19.35%) developed severe disease and became critically ill. Olfactory dysfunction appeared before the other symptoms in 21.43% of cases. The proportion of females with olfactory and gustatory dysfunction was higher than that of males (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The incidence of olfactory and gustatory dysfunction was much lower than that reported abroad; the prognosis of patients with olfactory dysfunction is relatively favorable; olfactory and gustatory dysfunction can be used as a sign for early screening; females are more prone to olfactory and gustatory dysfunction.<\/jats:p><\/jats:sec>","DOI":"10.1002\/wjo2.5","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T19:53:03Z","timestamp":1655495583000},"page":"297-301","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Olfactory and gustatory dysfunctions of COVID\u201019 patients in China: A multicenter study"],"prefix":"10.1002","volume":"8","author":[{"given":"Jianhui","family":"Li","sequence":"first","affiliation":[{"name":"College of Otolaryngology Head and Neck Surgery Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"},{"name":"Department of Otolaryngology Head and Neck Surgery Chinese PLA General Hospital Hainan Hospital  Sanya China"},{"name":"Hainan Clinical Research Center for Otolaryngologic Diseases  Sanya China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery General Hospital of Central Theater Command  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enqiang","family":"Qin","sequence":"additional","affiliation":[{"name":"Treatment and Research Center for Infectious Diseases The Fifth Medical Center of Chinese PLA General Hospital  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