{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T05:49:37Z","timestamp":1766382577722,"version":"3.48.0"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T00:00:00Z","timestamp":1766275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["World j. otorhinolaryngol.-head neck surg."],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pott's puffy tumor (PPT) is a rare but serious sequela of frontal sinusitis characterized by osteomyelitis of the frontal bone with subperiosteal abscess formation. Surgical management has traditionally been delayed until resolution of the acute infection. This scoping review evaluates the safety and outcomes of performing \u201cHot\u201d Draf III (modified Lothrop) surgery during the acute phase of PPT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A review was conducted in accordance with PRISMA guidelines. Literature searches were performed across PubMed, Embase, Scopus, and\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      without date restriction. Eligible studies included patients undergoing Draf III surgery acutely (within 28 days of presentation) for PPT. Data were extracted on demographics, surgical approach, complications, and reintervention rates. Pooled analysis was performed using a random\u2010effects model with Freeman\u2013Tukey transformation to stabilize variance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Five studies met the inclusion criteria, encompassing nine patients (seven males, two females; mean age 50.3 years). All underwent acute Draf III surgery, primarily via endoscopic approaches (88.9%). Meta\u2010analysis demonstrated a pooled complication rate of 0% (95% CI: 0%\u201340%) and a reintervention rate of 3% (95% CI: 0%\u201371%), with no significant heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u20090%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\u201cHot\u201d Draf III surgery appears to be a safe and effective management option for PPT during the acute phase, offering low complication and reintervention rates. While these findings support early surgical intervention, larger, prospective studies are required to validate long\u2010term outcomes and define patient selection criteria.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjo2.70076","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T05:45:01Z","timestamp":1766382301000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Draf III in the Acute Phase of Pott's Puffy Tumor: A Scoping Review"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7816-323X","authenticated-orcid":false,"given":"Sahil","family":"Kakar","sequence":"first","affiliation":[{"name":"Department of ENT and Skull Base Surgery, Queen Elizabeth Hospital Birmingham University Hospitals Birmingham Foundation Trust Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9722-0365","authenticated-orcid":false,"given":"Haris","family":"Ali","sequence":"additional","affiliation":[{"name":"Queen's Medical Centre Nottingham University Hospitals NHS Trust Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husnaa Fathima Ali Azamathullah","family":"Khan","sequence":"additional","affiliation":[{"name":"Glenfield Hospital Leicester Hospitals Foundation Trust, NHS Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rameez","family":"Amjad","sequence":"additional","affiliation":[{"name":"Department of Medical Education Aberdeen University Medical School Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshara","family":"Sharma","sequence":"additional","affiliation":[{"name":"University Hospitals Birmingham Foundation Trust Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Daoud","family":"Tariq","sequence":"additional","affiliation":[{"name":"Foundation University Medical College Islamabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Sohaib","family":"Shahid","sequence":"additional","affiliation":[{"name":"Medical College Aga Khan University Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahzada Khuram","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of ENT and Skull Base Surgery, Queen Elizabeth Hospital Birmingham University Hospitals Birmingham Foundation Trust Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haissan","family":"Iftikhar","sequence":"additional","affiliation":[{"name":"Department of ENT Northamptonshire Healthcare NHS Foundation Trust  Northamptonshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1007\/s00405-020-05980-2","article-title":"Draf III Frontal Sinus Surgery for the Treatment of Pott's Puffy Tumour in Adults: Our Case Series and a Review of Frontal Sinus Anatomy Risk Factors","volume":"277","author":"Pendolino A. L.","year":"2020","journal-title":"European Archives of Oto\u2010Rhino\u2010Laryngology"},{"key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.bjorl.2016.08.005","article-title":"Pott's Puffy Tumor: Rare Complication of Sinusitis","volume":"86","author":"Costa L.","year":"2020","journal-title":"Brazilian Journal of Otorhinolaryngology"},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/S1473-3099(20)30684-8","article-title":"Pott's Puffy Tumour: A Rare and Life\u2010Threatening Disease","volume":"20","author":"Ikoma N.","year":"2020","journal-title":"Lancet Infectious Diseases"},{"key":"e_1_2_12_5_1","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.amjmed.2008.08.018","article-title":"Pott's Puffy Tumor","volume":"121","author":"Forgie S. E.","year":"2008","journal-title":"American Journal of Medicine"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.XOCR.2019.01.007"},{"key":"e_1_2_12_7_1","doi-asserted-by":"crossref","first-page":"870S","DOI":"10.1177\/01455613211039031","article-title":"Pott's Puffy Tumor","volume":"100","author":"Tibesar R. J.","year":"2021","journal-title":"Ear, Nose, & Throat Journal"},{"key":"e_1_2_12_8_1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3342\/ceo.2012.5.2.112","article-title":"Endoscopic Endonasal Treatment of a Pott's Puffy Tumor","volume":"5","author":"Jung J.","year":"2012","journal-title":"Clinical and Experimental Otorhinolaryngology"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000150681.68355.8"},{"key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/wjo2.6","article-title":"The Draf III Procedure: A Review of Indications and Techniques","volume":"8","author":"Noller M.","year":"2022","journal-title":"World Journal of Otorhinolaryngology \u2010 Head and Neck Surgery"},{"key":"e_1_2_12_11_1","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews","volume":"372","author":"Page M. J.","year":"2021","journal-title":"BMJ"},{"key":"e_1_2_12_12_1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000506225","article-title":"A Rare Case of Palpebral Cellulitis, a Variation of Pott's Puffy Tumor","volume":"11","author":"Yamamoto M.","year":"2020","journal-title":"Case Reports in Ophthalmology"},{"key":"e_1_2_12_13_1","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1177\/1945892420959587","article-title":"Treatment of Frontal Sinus Osteomyelitis in the Age of Endoscopy","volume":"35","author":"Thompson H. M.","year":"2021","journal-title":"American Journal of Rhinology & Allergy"},{"key":"e_1_2_12_14_1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1177\/0003489417698497","article-title":"Minimally Invasive Surgery for Pott's Puffy Tumor: Is It Time for a Paradigm Shift in Managing a 250\u2010Year\u2010Old Problem","volume":"126","author":"Leong S. C.","year":"2017","journal-title":"Annals of Otology, Rhinology, & Laryngology"},{"key":"e_1_2_12_15_1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/0022-3859.32212","article-title":"Pott's Puffy Tumor Following an Insect Bite","volume":"53","author":"Raja V.","year":"2007","journal-title":"Journal of Postgraduate Medicine"},{"key":"e_1_2_12_16_1","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1093\/milmed\/usad291","article-title":"Pott's Puffy Tumor: A Rare, Life\u2010Threatening Presentation of Periorbital Edema","volume":"188","author":"Kuhar B. G.","year":"2023","journal-title":"Military Medicine"},{"key":"e_1_2_12_17_1","article-title":"Pott's Puffy Tumor in an Adult Female: A Case Report in a Rare Demographic","volume":"14","author":"Hitt N.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_12_18_1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/08998280.2017.11929575","article-title":"Pott Puffy Tumor","volume":"30","author":"Sharma P.","year":"2017","journal-title":"Baylor University Medical Center Proceedings"},{"key":"e_1_2_12_19_1","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/632464","article-title":"Extensive Frontoparietal Abscess: Complication of Frontal Sinusitis (Pott's Puffy Tumor)","volume":"2014","author":"Lauria R. A.","year":"2014","journal-title":"Case Reports in Otolaryngology"},{"key":"e_1_2_12_20_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjoto.2022.103529","article-title":"Pott's Puffy Tumor: A Comprehensive Review of the Literature","volume":"43","author":"Rohde R. L.","year":"2022","journal-title":"American Journal of Otolaryngology"},{"key":"e_1_2_12_21_1","doi-asserted-by":"crossref","DOI":"10.1002\/ccr3.70087","article-title":"Functional Endoscopic Sinus Surgery in Management of Pott's Puffy Tumor in a Pregnant Woman: A Clinical Case Report and Literature Review","volume":"13","author":"Dehghan Manshadi S. A.","year":"2025","journal-title":"Clinical Case Reports"},{"key":"e_1_2_12_22_1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.radcr.2024.10.128","article-title":"A Rare Case Report: Pott's Puffy Tumor and Lemierre's Syndrome With Intracranial Complications in an Adult Male","volume":"20","author":"Azouz I.","year":"2025","journal-title":"Radiology Case Reports"},{"key":"e_1_2_12_23_1","first-page":"119","article-title":"Combined Endonasal and Percutaneous Endoscopic Approach to Pott's Puffy Tumour","volume":"34","author":"el\u2010Silimy O.","year":"1996","journal-title":"Rhinology"},{"key":"e_1_2_12_24_1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1177\/00034894241298749","article-title":"Enlarged Frontal Sinusotomy and Chronic Rhinosinusitis With Nasal Polyps: An Effective Strategy to Control the Disease","volume":"134","author":"Saccardo T.","year":"2025","journal-title":"Annals of Otology, Rhinology, & Laryngology"},{"key":"e_1_2_12_25_1","article-title":"Pott Puffy Tumor in Adults: The \u03a4iming of Surgical \u0399ntervention","volume":"12","author":"Sideris G.","year":"2020","journal-title":"Cureus"}],"container-title":["World Journal of Otorhinolaryngology - Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/wjo2.70076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T05:45:04Z","timestamp":1766382304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/wjo2.70076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,21]]},"references-count":24,"alternative-id":["10.1002\/wjo2.70076"],"URL":"https:\/\/doi.org\/10.1002\/wjo2.70076","archive":["Portico"],"relation":{},"ISSN":["2095-8811","2589-1081"],"issn-type":[{"value":"2095-8811","type":"print"},{"value":"2589-1081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,21]]},"assertion":[{"value":"2025-10-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"wjo2.70076"}}