{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T08:22:33Z","timestamp":1758702153117,"version":"3.40.5"},"reference-count":73,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T00:00:00Z","timestamp":1702166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Obesity worsens various gastrointestinal pathologies. While bariatric surgery ameliorates obesity, it substantially modifies the gastrointestinal system depending on surgery type, with limited data on subsequent impact on obesity\u2010related gastrointestinal admissions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the 2012\u20132014 Nationwide Readmission Database, we included individuals with obesity who received vertical sleeve gastrectomy (VSG), Roux\u2010en\u2010Y gastric bypass (RYGB), or hernia repair (HR\u2013control surgery). Our main focus was the adjusted odds ratio (aOR) for gastrointestinal inpatient admissions within 6\u00a0months following surgery compared to the 6\u00a0months preceding it, while controlling for several confounding factors. Gastrointestinal admissions were grouped into postoperative complications or obesity\u2010associated gastrointestinal conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our cohort included 140,103 adults with RYGB, 132,253 with VSG, and 12,436 HR controls. Postoperative gastrointestinal complications were most common after RYGB, prominently obstruction (aOR\u00a0=\u00a033.17, 95%CI: 18.01, 61.10), and <jats:italic>Clostridium difficile<\/jats:italic> infection (aOR: 12.52, 95%CI: 6.22, 25.19). VSG also saw significantly increased but less frequent similar conditions. Notably, for gastrointestinal conditions associated with obesity, acute pancreatitis risk was higher post\u2010VSG (aOR\u00a0=\u00a06.26, 95%CI: 4.02, 9.73). Post\u2010RYGB patients were most likely to be admitted for cholelithiasis with cholecystitis (aOR: 4.15, 95% CI: 3.24, 5.31), followed by chronic liver disease (aOR: 3.00, 95% CI: 2.33, 3.87). The risk of noninfectious colitis admissions was threefold higher after RYGB and VSG. No gastrointestinal conditions showed an increase after HR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite weight loss, bariatric surgery was associated with an increased risk of hepato\u2010pancreatobiliary and colitis admissions related to obesity in the first six postoperative months, with considerable variations in rates of gastrointestinal conditions by surgery type.<\/jats:p><\/jats:sec>","DOI":"10.1002\/wjs.12013","type":"journal-article","created":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T03:49:59Z","timestamp":1702698599000},"page":"175-185","source":"Crossref","is-referenced-by-count":1,"title":["The impact of bariatric surgery on admissions for gastrointestinal complications and conditions associated with obesity: A nationwide study"],"prefix":"10.1002","volume":"48","author":[{"given":"Arsheya","family":"Patel","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Department of Internal Medicine Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barham K.","family":"Abu Dayyeh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gokulakrishnan","family":"Balasubramanian","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Department of Internal Medicine Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Hinton","sequence":"additional","affiliation":[{"name":"Division of Biostatistics College of Public Health The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somashekar G.","family":"Krishna","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Department of Internal Medicine Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacy","family":"Brethauer","sequence":"additional","affiliation":[{"name":"Department of Surgery Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8646-8370","authenticated-orcid":false,"given":"Hisham","family":"Hussan","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine University of California, Davis  Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.08.063"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.12.052"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1909301"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010022\u201007589\u20103"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2013.3654"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.14.1724"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.15.1960"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.10706"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2004.118"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.10.035"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010011\u20101620\u20106"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2011.03.006"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200225"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2016.2317"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(23)00634\u20107"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2016.03.060"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010004\u20108804\u20102"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.9.957"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2006.03.004"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41424\u2010018\u20100045\u20100"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695\u2010018\u20103131\u20101"},{"issue":"1","key":"e_1_2_9_23_1","first-page":"25","article-title":"Wound Infections in Abdominal Surgery. 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