{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:29:45Z","timestamp":1790890185287,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T00:00:00Z","timestamp":1727568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The Lichtenstein technique is the gold standard for adult open inguinal hernia repair with mesh. The Desarda technique emerged in 2001 as a novel, promising non\u2010mesh technique that has demonstrated low recurrence and postoperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched MEDLINE, the Cochrane Central Register of Clinical Trials, and Embase for randomized controlled trials (RCT) published until April 2024. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using a random\u2010effects model. Heterogeneity was assessed using Cochran's <jats:italic>Q<\/jats:italic> test and <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> statistics, with <jats:italic>p<\/jats:italic>\u2010values &lt;0.10 and <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>&gt;25% considered significant. Statistical analysis was performed using the R software, version 4.1.2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighteen RCTs comprising 1756 patients were included, of whom 861 (49%) were submitted to Desarda and 895 (51%) were submitted to Lichtenstein. Desarda was associated with lower seroma rates (OR 0.55; 95% CI 0.35\u20130.89; and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.014), less operative time (MD \u22128.6\u00a0min; 95% CI \u221214.5 to \u22122.8; and <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01), lower postoperative pain on day one (MD \u22121.3 VAS score; 95% CI \u22122.3 to \u22120.3; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01) or chronic pain (OR 0.32; 95% CI 0.12\u20130.88; and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.028), and faster return\u2010to\u2010work activities (MD \u22122.1\u00a0days; 95% CI \u22123.7 to \u22120.6; and <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). The recurrence rate was 1.4% for Desarda versus 2.1% for Lichtenstein, with no statistical difference between techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this meta\u2010analysis, Desarda significantly decreases seroma operative time, postoperative pain on day 1, chronic pain, and return\u2010to\u2010work activities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/wjs.12360","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T01:30:36Z","timestamp":1727659836000},"page":"2615-2628","source":"Crossref","is-referenced-by-count":6,"title":["Desarda versus Lichtenstein inguinal hernia repair: A meta\u2010analysis of randomized controlled trials"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2960-3810","authenticated-orcid":false,"given":"Bernardo Fontel","family":"Pompeu","sequence":"first","affiliation":[{"name":"Department of General Surgery Heliopolis Hospital  S\u00e3o Paulo 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