{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T14:59:21Z","timestamp":1763564361106,"version":"3.40.5"},"reference-count":50,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,20]],"date-time":"2024-10-20T00:00:00Z","timestamp":1729382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Global disparities in valvular surgery services exist. Cost\u2010effectiveness analysis (CEA) and cost\u2010utility analysis can be used to guide national investment decisions. This scoping review aims to synthesize economic evaluations for valvular surgery by income settings and provide recommendations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic literature review identified primary CEAs or CUAs in English comparing surgical management strategies for valvular heart disease. MEDLINE, Embase, CINAHL, Web of Science, and Business Source Complete were searched using keywords \u201cvalvular surgery,\u201d \u201cvalve disease,\u201d \u201ccost\u2010effectiveness,\u201d and \u201ccost\u2010benefit analysis\u201d. Articles comparing outcomes or costs only were excluded. Search results were uploaded and screened on COVIDENCE. Variables from eligible articles were charted in a spreadsheet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty articles were eligible, six from low\u2010 and middle\u2010income countries (LMICs) and 14 from high\u2010income countries (HICs). In HICs, the top conditions were degenerative aortic valve disease (7\/14) and mitral valve disease (4\/14) compared to congenital (2\/6) and rheumatic heart diseases (2\/6) in LMICs. HICs evaluated new technologies and techniques, whereas LMICs compared different valve types or surgery versus no intervention. Most articles used published studies (12\/20) or databases (7\/20) to conduct their CEA and quality\u2010adjusted life years was the most common effectiveness measure (12\/20). Comparator interventions were cost\u2010effective in all LMIC articles and in 8\/14 for HICs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Economic evaluations are mostly conducted in HICs and for adult conditions. More analyses in LMICs are needed. This can be facilitated by maintaining databases, documenting costs, and implementing quality of life assessments.<\/jats:p><\/jats:sec>","DOI":"10.1002\/wjs.12381","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T03:19:05Z","timestamp":1729480745000},"page":"2571-2585","source":"Crossref","is-referenced-by-count":2,"title":["Cost\u2010effectiveness analysis of valvular surgery in high\u2010 and low\u2010 to middle\u2010income countries: A scoping review"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3468-7018","authenticated-orcid":false,"given":"Vongai","family":"Mlambo","sequence":"first","affiliation":[{"name":"Stanford University School of Medicine Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Hyles","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine Stanford University  Stanford 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