{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:00:36Z","timestamp":1788321636320,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG076834"],"award-info":[{"award-number":["R01AG076834"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2025,3]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Hyperparathyroidism (HPT) is common in end\u2010stage kidney disease and resolves in less than half of kidney transplant (KT) recipients. The ideal timing of parathyroidectomy (PTX), before or after KT, remains unclear. We sought to understand differences in morbidity and mortality after PTX pre\u2010KT and post\u2010KT.<\/jats:p><\/jats:sec>Methods<\/jats:title>We identified adult patients who underwent PTX pre\u2010KT or post\u2010KT between 2012 and 2021 utilizing the National Surgical Quality Improvement Program database. Demographics, clinical characteristics, morbidity, and mortality were compared. Adjusted logistic regression with propensity score weighting assessed odds of 30\u2010day composite morbidity, major adverse cardiovascular events (MACE), readmission, and mortality.<\/jats:p><\/jats:sec>Results<\/jats:title>We identified 1972 patients who underwent PTX pre\u2010KT and 541 patients who underwent PTX post\u2010KT. Post\u2010KT HPT patients were older (mean age 53.9 v 48.2 and p<\/jats:italic>\u00a0<\u00a00.01) and more commonly White (45.3% v 32.3% and p<\/jats:italic>\u00a0<\u00a00.01) and diabetic (30.0% v 18.5% and p<\/jats:italic>\u00a0<\u00a00.01). In comparison, pre\u2010KT HPT patients were more commonly Black (53.2% v 30.1%), had American Society of Anesthesiologists (ASA) class 3\u20134 (98.0% v 89.6% and p<\/jats:italic>\u00a0<\u00a00.01), chronic obstructive pulmonary disease (4.2% v 1.5% and p<\/jats:italic>\u00a0<\u00a00.01), and congestive heart failure (4.4% v 1.1% and p<\/jats:italic>\u00a0<\u00a00.01). After adjusting for confounders, patients pre\u2010KT had 1.72\u2010fold increased odds of morbidity (95% confidence interval [CI]: 1.13\u20132.61), 8.39\u2010fold increased odds of MACE (95% CI: 1.13\u201362.18), and 2.07\u2010fold increased odds of readmission (95% CI: 1.38\u20133.10). There was no difference in mortality or risk of infections.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Patients who underwent PTX prior to KT were at significantly increased risk for 30\u2010day morbidity and MACE, but no different odds of mortality compared to PTX after KT. This can help inform decision\u2010making regarding timing of PTX in patients with HPT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/wjs.12468","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T02:50:00Z","timestamp":1737600600000},"page":"643-651","source":"Crossref","is-referenced-by-count":2,"title":["Surgical outcomes of parathyroidectomy for pre\u2010kidney transplantation versus post\u2010kidney transplantation patients"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7416-177X","authenticated-orcid":false,"given":"Darci C.","family":"Foote","sequence":"first","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Surgery Center for Outcomes Research (JSCOR) Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"You","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Surgery Center for Outcomes Research (JSCOR) Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy Z.","family":"Done","sequence":"additional","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennine","family":"Weller","sequence":"additional","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Stemme","sequence":"additional","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Moreno","sequence":"additional","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilah F.","family":"Morris\u2010Wiseman","sequence":"additional","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aarti","family":"Mathur","sequence":"additional","affiliation":[{"name":"Collaborative Outcomes Research in Endocrine Surgery (CORES) Lab Division of Endocrine Surgery Department of Surgery Johns Hopkins University School of Medicine Baltimore Maryland 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