{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:12:00Z","timestamp":1770743520365,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pancreatic trauma is rare, accounting for only 0.2% of all trauma cases, and reports on long\u2010term endocrine outcomes are scarce. Patients who undergo pancreatic resection may develop diabetes mellitus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To summarize the available literature reporting the incidence of diabetes mellitus (DM) after pancreatic trauma and to evaluate potential influences on the incidence rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We searched in PubMed and Embase for studies published between 1990 and July 2025 that enrolled patients with trauma of the pancreas and reported data on new\u2010onset DM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Out of 906 identified records, six studies with a total of 297 patients with pancreatic trauma. The overall cumulative incidence of new\u2010onset DM is 5.7% (95% confidence interval [CI]: 3.4%\u20139.0%). DM developed in 8.2% (95% CI: 4.4%\u201313.6%) of patients who underwent (partial) pancreatic resection and in 2.9% (95% CI: 0.8%\u20137.4%) of patients treated nonoperatively. For low\u2010grade injuries, the incidence of DM was 5.5% (95% CI: 2.0%\u201311.5%) compared to 11.1% (95% CI: 4.9%\u201320.7%) for high\u2010grade injuries. The time until new\u2010onset diabetes mellitus was detailed in one study with 15 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Based on the available literature, the estimated overall incidence of DM after pancreatic trauma is 5.7%. High\u2010grade pancreatic injury seems to increase the risk of developing new\u2010onset DM, which is possibly influenced by their frequent surgical treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjs.70056","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T15:49:12Z","timestamp":1755618552000},"page":"2940-2951","source":"Crossref","is-referenced-by-count":1,"title":["New\u2010Onset Diabetes Mellitus Following Pancreatic Injury: A Systematic Review"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9633-3807","authenticated-orcid":false,"given":"V. P. C.","family":"van Zon","sequence":"first","affiliation":[{"name":"Department of Trauma Surgery Leiden University Medical Center  Leiden the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7064-2947","authenticated-orcid":false,"given":"M. C.","family":"Tol","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Leiden University Medical Center  Leiden the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7154-9514","authenticated-orcid":false,"given":"P.","family":"Krijnen","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery Leiden University Medical Center  Leiden the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7162-1467","authenticated-orcid":false,"given":"V. A. L.","family":"Huurman","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery Leiden University Medical Center  Leiden the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4371-2246","authenticated-orcid":false,"given":"D. A.","family":"Ruess","sequence":"additional","affiliation":[{"name":"Department of General and Visceral Surgery Center for Surgery Medical Center University of Freiburg  Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9952-3079","authenticated-orcid":false,"given":"I. 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