{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:23:04Z","timestamp":1787858584281,"version":"build-2784847793"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100007206","name":"Kaibara Morikazu Medical Science Promotion Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007206","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020109","name":"Fukuoka Public Health Promotion Organization Cancer Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Remnant gastric cancer (RGC) is known to have a poorer prognosis compared to primary gastric cancer. Inflammation\u2010based prognostic scores (IBPSs), which reflect systemic inflammation and nutritional status, have recently emerged as useful prognostic markers in various malignancies. However, their significance in RGC remains unclear due to the rarity of the disease and the limited number of cases available at single institutions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective multicenter study of 135 patients who underwent surgery for RGC between 2013 and 2024 at Kyushu University and four affiliated hospitals. After excluding nine patients with synchronous malignancies or noncurative resections, 126 patients were included in the final analysis. Associations between IBPSs\u2014including the neutrophil\u2010to\u2010lymphocyte ratio (NLR), platelet\u2010to\u2010lymphocyte ratio (PLR), C\u2010reactive protein\u2010to\u2010albumin ratio (CAR), and prognostic nutritional index (PNI)\u2014and both short\u2010 and long\u2010term outcomes were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Receiver operating characteristic (ROC) analysis determined optimal cutoff values for each IBPS. Kaplan\u2013Meier analysis revealed that PLR \u2265\u00a0195 and PNI &lt;\u00a043.5 were significantly associated with poorer overall survival (OS) (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.008 and\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001, respectively). Multivariate analysis identified PLR \u2265\u00a0195 and PNI &lt;\u00a043.5 as independent predictors of poor OS and recurrence\u2010free survival (RFS). Additionally, PLR \u2265\u00a0260 was identified as an independent risk factor for postoperative complications (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.047).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PLR and PNI are independent prognostic markers for both OS and RFS in patients undergoing curative surgery for RGC. Elevated PLR also predicts postoperative complications, highlighting its potential role in perioperative risk stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjs.70111","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:24:46Z","timestamp":1758763486000},"page":"3195-3204","source":"Crossref","is-referenced-by-count":3,"title":["Prognostic Significance of Platelet\u2010Lymphocyte Ratio (PLR) and Prognostic Nutritional Index (PNI) in Remnant Gastric Cancer: A Multicenter Retrospective Study"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8977-9126","authenticated-orcid":false,"given":"Kensuke","family":"Kudou","sequence":"first","affiliation":[{"name":"Department of Surgery and Science Graduate School of Medical Sciences Kyushu University  Fukuoka Japan"},{"name":"Department of Gastroenterological Surgery The Cancer Institute Hospital of Japanese Foundation for Cancer Research  Tokyo 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Center  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomichi","family":"Koga","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery NHO Kyushu Cancer Center  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Hasuda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Clinical Research Institute Cancer Research Division National Hospital Organization Kyushu Medical Center  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotada","family":"Tajiri","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Clinical Research Institute Cancer Research Division National Hospital Organization Kyushu Medical Center  Fukuoka 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