{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T17:45:30Z","timestamp":1776015930890,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:00:00Z","timestamp":1773446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:00:00Z","timestamp":1773446400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence regarding the feasibility and outcomes of enhanced recovery after surgery (ERAS) programs in patients undergoing simultaneous colorectal resection and hepatectomy remains limited. This study aimed to evaluate the impact of ERAS implementation on perioperative and oncologic outcomes in patients undergoing simultaneous colorectal resection and hepatectomy for synchronous colorectal liver metastases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A single\u2010center retrospective cohort study was conducted involving 100 consecutive patients who underwent elective simultaneous colorectal resection and hepatectomy before (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a050) and after (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a050) ERAS implementation. Outcomes included postoperative complications, length of stay, hospital cost, disease\u2010free survival, and overall survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age was 63\u00a0years, and 55% were male. Rectal cancer was the primary tumor in 38 patients, and 18 patients required major hepatectomy. Baseline characteristics and operative details were comparable between the ERAS and conventional care groups. ERAS implementation significantly reduced postoperative complications (22% vs. 42% and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.032) and time to tolerate a solid diet (3 vs. 5\u00a0days and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001). Median postoperative length of stay was shorter in the ERAS group (6\u00a0days [IQR 5\u20139] vs. 8\u00a0days [IQR 6\u201316] and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.005). Average hospital cost was slightly lower with ERAS (4815 USD vs. 5298 USD and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.446). Five\u2010year overall and disease\u2010free survival rates were similar between groups (86.7% vs. 88.9%;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.583 and 44.4% vs. 48.9%;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.724, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ERAS implementation in simultaneous colorectal resection and hepatectomy resulted in shorter hospitalization, faster bowel recovery, and a modest reduction in cost, while maintaining comparable long\u2010term oncologic outcomes.<\/jats:p>\n                  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Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8728-045X","authenticated-orcid":false,"given":"Pornraksa","family":"Ovartchaiyapong","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok 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