{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:56:57Z","timestamp":1786978617784,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The choice between low anterior resection (LAR) and abdominoperineal resection (APR) for low rectal cancer involves complex trade\u2010offs between sphincter preservation and functional outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to compare overall quality of life (QoL), colorectal\u2010specific symptoms, and functional outcomes between LAR and APR at \u2265\u00a012\u00a0months post\u2010surgery and to identify influencing factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective cohort study included patients who underwent LAR or APR for low rectal cancer (\u2264\u00a05\u00a0cm from the anal verge) between January 2019 and December 2023. Patients completed validated questionnaires 12\u201360\u00a0months post\u2010surgery. Inverse probability of treatment weighting was employed to adjust for baseline imbalances.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 168 eligible patients, 142 (84.5%) completed assessments (LAR\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a078, APR\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a064). After adjustment, the mean global health status was 68.3\u00a0\u00b1\u00a018.5 for LAR versus 71.2\u00a0\u00b1\u00a016.8 for APR (adjusted mean difference \u22122.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.302). Major low\u2010anterior resection syndrome affected 44.9% of LAR patients, whereas 31.3% of APR patients reported poor stoma\u2010related QoL. Sexual dysfunction was prevalent in both groups. Neoadjuvant chemoradiotherapy and tumor distance \u2264\u00a03\u00a0cm predicted major LARS. LARS severity did not perfectly align with QoL impairment; 20.0% of patients with minor LARS reported poor QoL, whereas 22.9% with major LARS maintained good QoL.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>No clinically meaningful difference in overall QoL was observed between LAR and APR at long\u2010term follow\u2010up. However, procedure\u2010specific challenges exist; major LARS affects nearly half of LAR patients, and one\u2010third of APR patients report poor stoma\u2010related QoL. These findings support individualized surgical decision\u2010making based on patient priorities and risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjs.70396","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T13:15:23Z","timestamp":1780146923000},"page":"1775-1785","source":"Crossref","is-referenced-by-count":1,"title":["Postoperative Function and Quality of Life of Patients With Low Rectal Cancer: A Multidimensional Comparison Between Low Anterior Resection and Abdominoperineal Resection"],"prefix":"10.1002","volume":"50","author":[{"given":"Jing","family":"Ju","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Shanxi Provincial People's Hospital  Taiyuan Shanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1999-5621","authenticated-orcid":false,"given":"Yixin","family":"Li","sequence":"additional","affiliation":[{"name":"First Hospital of Shanxi Medical University  Taiyuan Shanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"He","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Shanxi Provincial People's Hospital  Taiyuan Shanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4805-0974","authenticated-orcid":false,"given":"Yonggang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Shanxi Provincial People's Hospital  Taiyuan Shanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2024.00388.0055"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15084"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.06.031"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010018\u20106738\u20105"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15205011"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrac085"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs5.50312"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/dcr.0000000000001583"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010015\u20101050\u20103"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13566"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15343"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.1998.16.1.139"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.5.365"},{"key":"e_1_2_12_15_1","volume-title":"EORTC 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