{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T07:07:25Z","timestamp":1783840045356,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The utility of intraoperative parathyroid hormone (IOPTH) monitoring during subtotal parathyroidectomy to predict long\u2010term intact PTH levels in kidney failure remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Diagnostic accuracy study in a cohort of 46 patients with severe, uncontrolled secondary hyperparathyroidism. IOPTH was measured before incision and at 10\u2010 and 30\u2010min post\u2010excision. Sensitivity, specificity, and AUC\u2010ROC were assessed for predicting surgical success\u2014defined as iPTH &lt;\u00a0300\u00a0pg\/mL (KDOQI criterion) over 6\u00a0months. We also assessed KDIGO criterion as secondary outcome (iPTH &lt;\u00a09\u00d7 the upper limit of normal, defined as 792\u00a0pg\/mL) All patients received postoperative calcium and active vitamin D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Surgical success was achieved in 37 (80%) patients using the KDOQI criterion. Compared with the failure group, the KDOQI success group had lower median 10\u2010min IOPTH (186\u00a0pg\/mL vs. 495\u00a0pg\/mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) and 30\u2010min IOPTH (112\u00a0pg\/mL vs. 495\u00a0pg\/mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). The 10\u2010min percentage decline in IOPTH was also greater in patients who experienced KDOQI success (91% vs. 85%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.008). AUCs for 10\u2010 and 30\u2010min IOPTH in predicting KDOQI success were 0.86 (95% CI: 0.72\u20131.00) and 0.86 (95% CI: 0.73\u20131.00), respectively. AUCs for percentage decline at 10 and 30\u00a0min were 0.78 (95% CI: 0.63\u20130.92,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.03) and 0.75 (95% CI: 0.60\u20130.92,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.02), respectively. A 10\u2010min IOPTH &lt;\u00a0270.7\u00a0pg\/mL yielded 89% sensitivity and 68% specificity for predicting KDOQI success. Using KDIGO criterion, 41 (89%) patients achieved surgical success, with similar trends observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In severe secondary hyperparathyroidism due to kidney failure, 10\u2010min IOPTH is a strong predictor of surgical success, with &lt;\u00a0270\u00a0pg\/mL suggesting better outcomes; percentage decline and 30\u2010min values add little benefit.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjs.70419","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T12:38:17Z","timestamp":1778762297000},"page":"1925-1936","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative Parathyroid Hormone Monitoring During Parathyroidectomy in Severe Secondary Hyperparathyroidism due to Kidney Failure"],"prefix":"10.1002","volume":"50","author":[{"given":"Juan C.","family":"Ram\u00edrez\u2010Sandoval","sequence":"first","affiliation":[{"name":"Department of Nephrology and Mineral Metabolism Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3463-6309","authenticated-orcid":false,"given":"Gabriel","family":"Cojuc\u2010Konigsberg","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vianca A.","family":"Canaviri\u2010Flores","sequence":"additional","affiliation":[{"name":"Hospital Obrero Nro 1 CNS  La Paz Bolivia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Zavala\u2010Miranda","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Mineral Metabolism Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abril","family":"Hern\u00e1ndez\u2010Calder\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Mineral Metabolism Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sof\u00eda","family":"Anaya\u2010S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5790-3671","authenticated-orcid":false,"given":"Rafael H.","family":"Perez\u2010Soto","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Alejandra","family":"Buerba","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Velazquez\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City 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