{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:18:49Z","timestamp":1789863529751,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Breast cancer is the most prevalent malignancy among women globally, and mastectomy often forms a critical part of its treatment. Breast reconstruction is an important aspect of post\u2010mastectomy care, contributing to improved psychological well\u2010being and quality of life. This study compares the outcomes of two distinct Latissimus Dorsi (LD) flap reconstruction techniques: one utilizing implant augmentation (LD\u2010I) and the other employing autologous fat graft (lipofilling) for volume restoration (LD\u2010L).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was conducted, analyzing 116 patients who underwent breast reconstruction with either the LD\u2010I or LD\u2010L technique between 2013 and May 2024. Data was collected from two centers in Brazil. The primary outcome was the rate of major complications, defined as those requiring surgical re\u2010intervention or hospital readmission. Secondary outcomes included the incidence of early (\u2264 6\u00a0months) and late (&gt; 6\u00a0months) complications and the correlation of clinical characteristics in regards to the complications, such as comorbidities and vices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study population comprised 50 patients in the LD\u2010I group and 66 patients in the LD\u2010L group. The mean age of patients was approximately 50\u00a0years in both groups. There were no significant differences between the groups regarding oncologic characteristics, including tumor stage, histological subtype, and receipt of neoadjuvant or adjuvant therapies. While the overall rate of major complications was not statistically different between the two groups (18% LD\u2010I vs. 7.6% LD\u2010L,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.079), specific complications varied. The LD\u2010I group exhibited a significantly higher rate of early infections (20% vs. 6.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.023) and a greater incidence of late reconstruction loss due to implant\u2010related issues (10% vs. 0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.013).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both LD\u2010I and LD\u2010L techniques provide viable options for breast reconstruction. However, the LD\u2010L technique demonstrated a lower risk of infection and reconstruction loss in this cohort. These findings suggest that LD\u2010L may offer a favorable alternative for minimizing specific complications and improving long\u2010term outcomes in post\u2010mastectomy breast reconstruction. However, these findings should be analyzed with caution and further prospective, randomized studies with larger sample sizes are warranted to confirm these observations and to identify specific patient subgroups that may benefit most from each technique.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjs.70494","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:27:07Z","timestamp":1785842827000},"page":"2539-2545","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Study of Myocutaneous Latissimus Dorsi Flap Breast Reconstruction With Implant Versus Lipofilling: Complication Rates and Risk Factors"],"prefix":"10.1002","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9859-6565","authenticated-orcid":false,"given":"Aline Prado","family":"de Almeida","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Irmandade da Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9478-5616","authenticated-orcid":false,"given":"Vilmar Marques","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Irmandade da Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Faculty of Medical Sciences of Santa Casa de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9899-9278","authenticated-orcid":false,"given":"Regis Rezende","family":"Paulinelli","sequence":"additional","affiliation":[{"name":"Department of Mastology Associa\u00e7\u00e3o de Combate ao C\u00e2ncer de Goi\u00e1s  Goi\u00e2nia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6894-3780","authenticated-orcid":false,"given":"Fabio","family":"Bagnoli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Irmandade da Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Faculty of Medical Sciences of Santa Casa de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Francisco","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Irmandade da Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Faculty of Medical Sciences of Santa Casa de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0589-1423","authenticated-orcid":false,"given":"Fabricio Palermo","family":"Brenelli","sequence":"additional","affiliation":[{"name":"Department Breast Oncology Universidade de Campinas  Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2899-7271","authenticated-orcid":false,"given":"Ivo Carelli","family":"Filho","sequence":"additional","affiliation":[{"name":"Department of Mastology Faculdade de Medicina do ABC  Santo Andr\u00e9 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5278-6883","authenticated-orcid":false,"given":"Tainara Rodrigues","family":"Miranda","sequence":"additional","affiliation":[{"name":"Department of Mastology Associa\u00e7\u00e3o de Combate ao C\u00e2ncer de Goi\u00e1s  Goi\u00e2nia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_14_3_1","first-page":"39","volume-title":"2023 Estimate: Cancer Incidence in Brazil","author":"Instituto Nacional de C\u00e2ncer (Brasil)","year":"2022"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.19141\/2237\u20103756.lifestyle.v4.n1.p99\u2010119"},{"key":"e_1_2_14_5_1","volume-title":"An\u00e1lise Comparativa entre interna\u00e7\u00f5es por mastectomia e cirurgia pl\u00e1stica de reconstru\u00e7\u00e3o mam\u00e1ria realizadas no sus entre os anos de 2010 \u00e0 2021. 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