{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T07:46:28Z","timestamp":1791963988358,"version":"4.3.4"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012533","name":"Minia University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012533","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Selective biliary cannulation at endoscopic retrograde cholangiopancreatography (ERCP) is difficult in up to 40% of native papillae and drives post\u2010ERCP pancreatitis (PEP) and incomplete common bile duct (CBD) clearance. Laparoendoscopic rendezvous (LERV) passes an antegrade transcystic guidewire across the papilla during laparoscopic cholecystectomy, a duodenoscope then completing sphincterotomy and extraction in one anesthetic. This study evaluated LERV in cholecystocholedocholithiasis pre\u2010stratified as anticipated difficult cannulation by preprocedural computed tomography (CT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a single\u2010centered prospective cohort study (June 2025\u2013June 2026; NCT07008170), 80 consecutive adults underwent contrast\u2010enhanced multidetector CT before surgery; the diagnosis rested on ultrasound, selective magnetic resonance cholangiopancreatography (MRCP) and biochemical criteria, MRCP not being universally available locally. Six radiologic predictors were recorded: worrisome periampullary diverticulum (PAD) score (0\u20132), papilla bulging, choledochoduodenal (CD) angle, distal CBD diameter, papilla location and a far\u2010distal CBD stone. The primary outcome was technical success, a feasibility endpoint analyzed separately from duct clearance; secondary outcomes were CBD clearance, PEP, morbidity, and 60\u2010day recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean age was 52.4\u00a0\u00b1\u00a013.1\u00a0years and 56.3% were women. Technical success was 92.5% (74\/80; 95% CI 84.6\u201397.2) and in\u2010admission complete CBD clearance 95.0% (76\/80). PEP occurred in 3\/80 (3.8%; all mild), post\u2010sphincterotomy bleeding and bile leak in 2\/80 each (2.5%), cholangitis in 3\/80 (3.8%) and perforation in 1\/80 (1.3%), with no 30\u2010day mortality. Technical success fell stepwise with the cumulative number of CT risk factors (Cochran\u2013Armitage\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001); a worrisome PAD score of 2 (odds ratio 9.4, 95% CI 1.7\u201352.8;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.011) and a CD angle \u2264\u00a020\u00b0 (odds ratio 6.8, 95% CI 1.3\u201335.4;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.024) independently predicted failure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a cohort whose papillary anatomy was characterized beforehand by CT, LERV achieved high in\u2010admission CBD clearance with a low rate of mild PEP and no mortality. The CT features were associated with, but did not themselves produce, technical success; read from a CT already obtained for a clinical indication they may assist case selection, theater planning and consent. Where MRCP is universally available these measurements should be validated on that platform, and the associations require external validation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>ClinicalTrials.gov NCT07008170 (registered 15 June 2025)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/wjs.70575","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:32:04Z","timestamp":1790091124000},"page":"2927-2936","source":"Crossref","is-referenced-by-count":0,"title":["Laparoendoscopic Rendezvous for Difficult Cholecystocholedocholithiasis: A Prospective Cohort Study With Computed Tomography\u2013Based Risk Stratification"],"prefix":"10.1002","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2234-7561","authenticated-orcid":false,"given":"Saleh K.","family":"Saleh","sequence":"first","affiliation":[{"name":"Department of Surgery Faculty of Medicine Minia University  Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimaa S.","family":"Elsharkawy","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Faculty of Medicine Minia University  Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman M.","family":"Hassanen","sequence":"additional","affiliation":[{"name":"Department of Surgery Faculty of Medicine Minia University  Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.121657"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.03.005"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i37.13382"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003327.pub4"},{"key":"e_1_2_13_6_1","volume-title":"Gallstone Disease: Diagnosis and Management","author":"National Institute for Health and Care Excellence","year":"2014"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2018.10.001"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.097543"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i45.4993"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010018\u20106286\u2010x"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.02.052"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0016\u20105107(93)70011\u20105"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000246913.74870.fc"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010005\u20100356\u20106"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/sla.0b013e3182456ec0"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.2844"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010013\u20103237\u20104"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100042\u2010108641"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101075\u20104080"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v11.i1.5"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2011.01.019"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009662.pub2"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.03.933"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0284185120909334"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129689\u2010200608000\u201000002"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102004\u2010826043"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v8.i6.282"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(07)61602\u2010X"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.09.041"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.02.053"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0016\u20105107(91)70740\u20102"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102012\u2010302779"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.512"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.261"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/wjs.70575","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/wjs.70575","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/wjs.70575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T07:02:48Z","timestamp":1791961368000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/wjs.70575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,22]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/wjs.70575"],"URL":"https:\/\/doi.org\/10.1002\/wjs.70575","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,22]]}}}