{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T10:49:14Z","timestamp":1781779754151,"version":"3.54.5"},"reference-count":154,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T00:00:00Z","timestamp":1640131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81930050"],"award-info":[{"award-number":["81930050"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wires.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["WIREs Nanomed Nanobiotechnol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nanozymes are nanomaterials with enzyme\u2010like characteristics, which catalyze the conversion of enzyme substrates and follow enzymatic kinetics under physiological conditions. As a new generation of artificial enzymes, nanozymes provide alternative approaches for those upon enzymatic catalysis. Compared with natural enzymes, nanozymes have the advantages of simple preparation, good stability and low cost, which makes nanozymes promising for application in many fields, such as antimicrobial infection treatment. Many studies have reported that nanozymes are capable of killing a number of pathogenic bacteria with resistance, fungi as well as viruses, and have shown great curative effects for diseases caused by these pathogens. Herein, we summarize the application of nanozymes for antibacterial, antiviral, and antifungal therapies and outline the issues needing resolution in the future.<\/jats:p><jats:p>This article is categorized under:<jats:list list-type=\"simple\">\n<jats:list-item><jats:p>Therapeutic Approaches and Drug Discovery &gt; Nanomedicine for Infectious Disease<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1002\/wnan.1769","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T04:32:05Z","timestamp":1640233925000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Catalytic antimicrobial therapy using nanozymes"],"prefix":"10.1002","volume":"14","author":[{"given":"Qian","family":"Wang","sequence":"first","affiliation":[{"name":"CAS Engineering Laboratory for Nanozyme Institute of Biophysics, Chinese Academy of Sciences  Beijing China"},{"name":"Graduate School of University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Jiang","sequence":"additional","affiliation":[{"name":"CAS Engineering Laboratory for Nanozyme Institute of Biophysics, Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0265-4027","authenticated-orcid":false,"given":"Lizeng","family":"Gao","sequence":"additional","affiliation":[{"name":"CAS Engineering Laboratory for Nanozyme Institute of Biophysics, Chinese Academy of Sciences  Beijing China"},{"name":"Nanozyme Medical Center, School of Basic Medical Sciences Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0TB00894J"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS90064A"},{"key":"e_1_2_11_4_1","first-page":"186","article-title":"Infections caused by acinetobacter baumannii in recipients of hematopoietic stem cell transplantation","volume":"4","author":"Al\u2010Anazi K. 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