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Yet,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    can under certain circumstances undergo a shift from commensalism to pathogenicity. This transition is governed by fungal factors such as morphological transitions, environmental cues for instance relationships with gut microbiota and the host immune system.\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    utilizes distinct sets of regulatory programs to colonize or infect its host and to evade the host defense systems. Moreover, an orchestrated iron acquisition mechanism operates to adapt to specific niches with variable iron availability. Studies on regulatory networks and morphogenesis of these two distinct modes of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    growth, suggest that both yeast and hyphal forms exist in both growth patterns and the regulatory circuits are inter\u2010connected. Here, we summarize current knowledge about\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    commensal\u2010to\u2010pathogen shift, its regulatory elements and their contribution to human disease.\n                  <\/jats:p>","DOI":"10.1002\/yea.3550","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T20:26:54Z","timestamp":1612556814000},"page":"243-250","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Regulators of commensal and pathogenic life\u2010styles of an opportunistic fungus\u2014\n                    <scp>\n                      <i>Candida albicans<\/i>\n                    <\/scp>"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7974-0196","authenticated-orcid":false,"given":"Laxmi Shanker","family":"Rai","sequence":"first","affiliation":[{"name":"Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques Institut Pasteur, USC2019 INRA  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lasse Van","family":"Wijlick","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques Institut Pasteur, USC2019 INRA  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Elisabeth","family":"Bougnoux","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques Institut Pasteur, USC2019 INRA  Paris France"},{"name":"Unit\u00e9 de Parasitologie\u2010Mycologie, Service de Microbiologie Clinique H\u00f4pital Necker\u2010Enfants\u2010Malades, Assistance Publique des H\u00f4pitaux de Paris (APHP)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3970-4825","authenticated-orcid":false,"given":"Sophie","family":"Bachellier\u2010Bassi","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques Institut Pasteur, USC2019 INRA  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6235-3886","authenticated-orcid":false,"given":"Christophe","family":"d'Enfert","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques Institut Pasteur, USC2019 INRA  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2014.03.003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00915-18"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1567-1364.2009.00570.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1006353"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000612"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/21688370.2019.1612661"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13320"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006699"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00186-06"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-842X(01)02094-7"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E05-06-0502"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002956"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2011.07.005"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2016.08.006"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.18981"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.10.5953-5959.2000"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.3.971-978.2000"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.4084\/mjhid.2011.001"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E03-11-0782"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E12-02-0094"},{"key":"e_1_2_9_22_1","first-page":"198","article-title":"Microbiology","volume":"338","author":"Ezenwa V. 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