{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T21:26:26Z","timestamp":1757453186951,"version":"3.37.3"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T00:00:00Z","timestamp":1596067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001343","name":"University of Pretoria","doi-asserted-by":"publisher","award":["V089\u201017"],"award-info":[{"award-number":["V089\u201017"]}],"id":[{"id":"10.13039\/501100001343","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoo Biology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The histological effect on the felid uterus of sterilization, via ovariectomy or salpingectomy, is currently unknown. To investigate the association of ovariectomy or salpingectomy with uterine health, it is first necessary to establish if changes are distributed evenly throughout the uterus. Both laparoscopic ovariectomy and salpingectomy with concurrent sampling of the tip of the uterine horn are possible in the cheetah. Currently accepted practice for histopathological screening of the uterus utilizes four biopsy samples. It is not known whether this method accurately reflects the status of the entire uterus. In this study we histologically examined the uteri of six older cheetahs (one 7\u2010year\u2010old and five 10\u201310.5\u2010year\u2010old animals) via 21 tissue samples (three samples from seven different anatomical regions) per cheetah to determine overall uterine health. Although no defined lesions were detected, mild endometrial gland dilation, assumed to be of no functional consequence, was observed in multiple samples. The odds of observing this dilation was lowest in the uterine body and progressively increased in a cranial direction, being significantly higher at the tip of the uterine horns (OR\u2009=\u200911.5; 95% CI, 2.0\u201065.1;<jats:italic>p<\/jats:italic>\u2009=\u20090.006). This supported the reliability of sampling the tip of the uterine horn to screen for endometrial gland dilation.<\/jats:p>","DOI":"10.1002\/zoo.21554","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T03:57:04Z","timestamp":1596167824000},"page":"325-333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Distribution of uterine histological changes in aged captive cheetahs (<i>Acinonyx jubatus<\/i>)"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9016-3142","authenticated-orcid":false,"given":"Miles J.","family":"Penfold","sequence":"first","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science University of Pretoria Onderstepoort South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0285-8679","authenticated-orcid":false,"given":"Martin L.","family":"Schulman","sequence":"additional","affiliation":[{"name":"Section of Reproduction, Department of Production Animal Studies, Faculty of Veterinary Science University of Pretoria Onderstepoort South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1368-1215","authenticated-orcid":false,"given":"Sarah","family":"Clift","sequence":"additional","affiliation":[{"name":"Section of Pathology, Department of Paraclinical Sciences, Faculty of Veterinary Science University of Pretoria Onderstepoort South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5651-5765","authenticated-orcid":false,"given":"Lisa","family":"du Plessis","sequence":"additional","affiliation":[{"name":"Idexx Laboratories Centurion South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2268-9748","authenticated-orcid":false,"given":"Peter N.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Section of Epidemiology, Department of Production Animal Studies, Faculty of Veterinary Science University of Pretoria Onderstepoort South Africa"},{"name":"Centre for Veterinary Wildlife Studies, Faculty of Veterinary Science University of Pretoria Onderstepoort South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8856-2363","authenticated-orcid":false,"given":"Marthinus J.","family":"Hartman","sequence":"additional","affiliation":[{"name":"Department of Companion Animal Clinical Studies, Faculty of Veterinary Science University of Pretoria Onderstepoort South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,30]]},"reference":[{"issue":"1","key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2460\/javma.1993.202.01.53","article-title":"Surgical techniques for neutering 6 to 14\u2010week\u2010old kittens","volume":"202","author":"Aronsohn M.","year":"1993","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2007.00780.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2010.08.024"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.1060337"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8290956"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2004.10.018"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12109"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-804088-1.00024-1"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.089417"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD16007"},{"issue":"1","key":"e_1_2_7_12_1","first-page":"65","article-title":"Effects of steroid hormones on uterine tissue remodeling of mouse menopause model","volume":"6","author":"Davoudi M.","year":"2015","journal-title":"Journal of Paramedical Sciences"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0531.2002.00358.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588402100307"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12026"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-1050-3-2"},{"key":"e_1_2_7_17_1","first-page":"61","article-title":"Development of a technique for transcervical collection of uterine tissue in bitches","volume":"57","author":"G\u00fcnzel\u2010Apel A. 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