{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:15:39Z","timestamp":1787170539703,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T00:00:00Z","timestamp":1608249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoo Biology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To curb agonistic interactions in a bachelor group of three male capybaras (\n                    <jats:italic>Hydrochoerus hydrochaeris<\/jats:italic>\n                    ), a single dose of leuprolide acetate (Lupron\u00ae) was used in an attempt to chemically sterilize the males. Concurrently, fecal androgen metabolite (FAM) concentrations were quantified via enzyme immunoassay to monitor changes in testosterone production after injection of the gonadotropin\u2010releasing hormone agonist. When Lupron proved ineffective in suppressing intraspecific aggression, surgical castration was performed on two males, with continued noninvasive endocrine monitoring. In all three capybaras, FAM concentrations increased initially as a result of the luteinizing hormone surge, but then decreased significantly following chemical sterilization. Surgical castration resulted in further, persistent declines in FAM concentrations in two males, while the third, intact male demonstrated a rise in FAM to pre\u2010Lupron concentrations at 8.5 and 9.5\u2010month postadministration. Despite successful suppression of sperm and testosterone production, intermale aggression continued, ultimately necessitating separation of the animals and transfer to other holding institutions. Under this set of conditions, a single Lupron dose was inadequate for suppressing intraspecific aggression in a group of three males with a pre\u2010established history of aggression.\n                  <\/jats:p>","DOI":"10.1002\/zoo.21586","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T16:29:04Z","timestamp":1608308944000},"page":"135-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of Lupron and surgical castration on fecal androgen metabolite concentrations and intermale aggression in capybaras (\n                    <i>Hydrochoerus hydrochaeris<\/i>\n                    )"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-6825","authenticated-orcid":false,"given":"Jennifer H.","family":"Yu","sequence":"first","affiliation":[{"name":"Global Health Program Smithsonian's National Zoo and Conservation Biology Institute Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Brown","sequence":"additional","affiliation":[{"name":"Center for Species Survival Smithsonian Conservation Biology Institute Front Royal Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Boisseau","sequence":"additional","affiliation":[{"name":"Center for Species Survival Smithsonian Conservation Biology Institute Front Royal Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Barthel","sequence":"additional","affiliation":[{"name":"Animal Care Sciences Smithsonian's National Zoo and Conservation Biology Institute Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzan","family":"Murray","sequence":"additional","affiliation":[{"name":"Global Health Program Smithsonian's National Zoo and Conservation Biology Institute Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,18]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"17","article-title":"Capybara care manual. silver spring","author":"AZA Rodent, Insectivore and Lagomorph TAG","year":"2018","journal-title":"MD: Association of Zoos and Aquariums"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1071\/AN09080"},{"key":"e_1_2_8_4_1","first-page":"275","article-title":"Control of reproduction and sex related behaviour in exotic wild carnivores with the GnRH analogue deslorelin: Preliminary observations","volume":"57","author":"Bertschinger H. 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