{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T01:48:23Z","timestamp":1770688103602,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T00:00:00Z","timestamp":1764460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T00:00:00Z","timestamp":1764460800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoo Biology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Klinefelter\u2032s syndrome is the most prevalent sex chromosomal disorder in humans and has been observed in various mammalian species. This article documents the case of a 25\u2010year\u2010old western lowland gorilla (\n                    <jats:italic>Gorilla gorilla gorilla<\/jats:italic>\n                    ) at Longleat Safari Park who was diagnosed with Klinefelter\u2032s syndrome. The study encompasses their diagnosis, behavioral assessment, and management strategies over twelve years. The behavioral profile includes neophobia, sensitivity to sounds, impaired problem\u2010solving abilities, mood swings, and atypical social interactions. Management practices tailored to his condition involved establishing a consistent daily routine, mitigating exposure to sudden noises, and pre\u2010emptive medical interventions at early signs of illness. These approaches have effectively addressed his unique needs and reduced stress\u2010related behaviours. This case study underscores the necessity for individualized care plans for nonhuman primates with Klinefelter\u2032s syndrome, providing a guide for future management of similar cases in captivity. The findings contribute to the limited knowledge of Klinefelter\u2032s syndrome in gorillas and highlight the importance of personalized and consistent management strategies to enhance the welfare of affected individuals.\n                  <\/jats:p>","DOI":"10.1002\/zoo.70043","type":"journal-article","created":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T18:08:51Z","timestamp":1764526131000},"page":"70-73","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Klinefelter\u2032S Syndrome in a Western Lowland Gorilla (\n                    <i>Gorilla gorilla gorilla<\/i>\n                    ) and Its Management"],"prefix":"10.1002","volume":"45","author":[{"given":"Matthew","family":"Hardy","sequence":"first","affiliation":[{"name":"Longleat Safari Park Warminster Wiltshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Bow","sequence":"additional","affiliation":[{"name":"Longleat Safari Park Warminster Wiltshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8787-3581","authenticated-orcid":false,"given":"Thomas C.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Longleat Safari Park Warminster Wiltshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-200105000-00007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021491"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-183X.2011.00705.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31014"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10577-010-9135-x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-2-11-615"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16678-6"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2008.08.007"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.06.019"},{"key":"e_1_2_8_11_1","unstructured":"Moody F.(2010) A Mystery Over Seattle\u2032s Celebrity Gorilla Bobo is Finally put to rest The Seattle Times. Available at:https:\/\/www.seattletimes.com\/pacific-nw-magazine\/a-mystery-over-seattles-celebrity-gorilla-bobo-is-finally-put-to-rest\/(Accessed: 4 March 2024)."},{"key":"e_1_2_8_12_1","unstructured":"NHS. (2017) Klinefelter Syndrome nhs.uk. Available at:https:\/\/www.nhs.uk\/conditions\/klinefelters-syndrome\/(Accessed: 4 March 2024)."},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000095241"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000321794"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mambio.2007.10.010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.GIM.0000095626.54201.D0"}],"container-title":["Zoo Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/zoo.70043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/zoo.70043","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/zoo.70043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T08:23:44Z","timestamp":1770625424000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/zoo.70043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,30]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/zoo.70043"],"URL":"https:\/\/doi.org\/10.1002\/zoo.70043","archive":["Portico"],"relation":{},"ISSN":["0733-3188","1098-2361"],"issn-type":[{"value":"0733-3188","type":"print"},{"value":"1098-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,30]]},"assertion":[{"value":"2024-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}