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The goal of the procedure was to create a teaser male for reproductive studies. Following chemical immobilization using a combination of medetomidine and thiafentanil, the giraffe underwent surgery with local anesthesia. The vas deferens were bilaterally located, dissected, and transected. Histopathological examination confirmed the presence of the vas deferens tissue. Five weeks post\u2010vasectomy, the giraffe was immobilized again for semen collection, confirming infertility. The giraffe was then used to confirm oestrus in synchronized females. Pre\u2010 and post\u2010vasectomy testosterone levels validated the procedure's effectiveness, confirming no change in the giraffe's normal behavior or attractiveness to females. The outcome was successful, with the giraffe rendered infertile post\u2010vasectomy.\n                  <\/jats:p>","DOI":"10.1002\/zoo.70046","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T10:19:51Z","timestamp":1765880391000},"page":"195-202","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First Vasectomy Procedure Successfully Performed on a Southern African Male Giraffe (\n                    <i>Giraffa camelopardalis giraffa<\/i>\n                    )"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6500-4625","authenticated-orcid":false,"given":"Francois","family":"Deacon","sequence":"first","affiliation":[{"name":"Department of Animal Science, Faculty of Natural and Agricultural Sciences University of the Free State Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willem","family":"Daffue","sequence":"additional","affiliation":[{"name":"Kroonstad Animal Hospital Kroonstad South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9765-0788","authenticated-orcid":false,"given":"Edward Collin","family":"Albertyn","sequence":"additional","affiliation":[{"name":"Absolute Genetics Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9628-4244","authenticated-orcid":false,"given":"Susanna Maria","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Absolute Genetics Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4553-6006","authenticated-orcid":false,"given":"Ayanda","family":"Maqhashu","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Natural and Agricultural Sciences University of the Free State Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7766-4062","authenticated-orcid":false,"given":"Jacquiline","family":"Goedhals","sequence":"additional","affiliation":[{"name":"Pathcare Bloemfontein South Africa"},{"name":"Department of AnatomicalPathology, Faculty of Health Sciences University of the Free State Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9105-2273","authenticated-orcid":false,"given":"Andri","family":"Grobbelaar","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Natural and Agricultural Sciences University of the Free State Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marike","family":"Badenhorst","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Natural and Agricultural Sciences University of the Free State Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,16]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Absolute Genetics \u201cSemen Collection \u201d published 2025 https:\/\/absolutegenetics.co.za\/semen-collection\/."},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-26797-5_8"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2019.901-908"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1997.210.05.675"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-1575-0.10016-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.58292\/ct.v15.9644"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2006.04.004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.12.039"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1530\/RAF-22-0005"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/tas\/txz174"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.21451\/1809-3000.RBRA2021.041"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.18203\/2349-2902.isj20221733"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12101290"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2023.114383"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/15627020.2015.1120643"},{"key":"e_1_2_8_17_1","unstructured":"El Toro 3 Electronic Ejaculator\/Immobiliser for Bulls and Rams. 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