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Red cells coated with complement in vitro by exposure to autologous low ionic strength serum or by the action of cold agglutinins did not induce complement fixation to normal red cells. It is postulated that the complement fixation to red cells in vivo observed in these patients is mediated by small amounts of red cell autoantibodies or antigen\u2010antibody complexes.<\/jats:p>","DOI":"10.1002\/art.1780120506","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T15:49:40Z","timestamp":1171468180000},"page":"498-503","source":"Crossref","is-referenced-by-count":2,"title":["Mechanism of complement binding by the red cell in rheumatoid arthritis"],"prefix":"10.1002","volume":"12","author":[{"given":"Bruce C.","family":"Gilliland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780100603"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/203535a0"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-117-29658"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105165"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1961.03620090010003"},{"key":"e_1_2_1_7_2","first-page":"175","article-title":"1958 revision of diagnostic criteria for rheumatoid arthritis","volume":"9","author":"Ropes M.","year":"1968","journal-title":"Bull. 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