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As observed by electron microscopy, significant numbers of these cells invaded the cartilage tissue and phagocytosed amorphous material which presumably contained immune complexes. In control cartilage from osteoarthritic, pyogenic, and normal subjects, only a few PMN were attached to the articular surface after incubation with PMN. These results demonstrate that immune complexes trapped in the superficial region of the rheumatoid articular cartilage may play an important role in the destruction of cartilage by the release of lysosomal enzymes from PMN.<\/jats:p>","DOI":"10.1002\/art.1780261204","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:53:46Z","timestamp":1171482826000},"page":"1434-1441","source":"Crossref","is-referenced-by-count":60,"title":["Interaction of polymorphonuclear leukocytes with immune complexes trapped in rheumatoid articular cartilage"],"prefix":"10.1002","volume":"26","author":[{"given":"Kazuhiro","family":"Ugai","sequence":"first","affiliation":[]},{"given":"Hitoshi","family":"Ishikawa","sequence":"additional","affiliation":[]},{"given":"Kazushi","family":"Hirohata","sequence":"additional","affiliation":[]},{"given":"Hirofumi","family":"Shirane","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2005,11,28]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"S193","article-title":"Lysosomes and rheumatoid joint inflammation","volume":"20","author":"Weissmann G","year":"1977","journal-title":"Arthritis Rheum (suppl)"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780180603"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780180606"},{"key":"e_1_2_1_5_2","first-page":"473","article-title":"Mechanism of trapping to immune complexes in joint collagenous tissues","volume":"22","author":"Jasin HE","year":"1975","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220407"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(195902)2:1<16::AID-ART1780020104>3.0.CO;2-9"},{"key":"e_1_2_1_8_2","first-page":"77","article-title":"Isolation of mononuclear cells and granulocytes from human blood","volume":"21","author":"B\u00f8yum A","year":"1968","journal-title":"Scand J Clin Lab Invest (suppl 97)"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.135.2.323"},{"key":"e_1_2_1_10_2","first-page":"615","article-title":"Antigen retention in joint tissues in antigen\u2010induced synovitis","volume":"16","author":"Hollister JR","year":"1974","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200508"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780210505"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.4049\/jimmunol.107.6.1535","article-title":"The immunologic release of constituents from neutrophilic leukocytes. 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The role of antibody and complement on non\u2010phagocytosable surfaces or phagocytosable particles","volume":"107","author":"Henson PM","year":"1971","journal-title":"J Immunol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197507000-00041"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.40.4.396"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106531"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780110203"},{"key":"e_1_2_1_18_2","first-page":"423","article-title":"Inhibition of neutrophil migration by sera from patients with rheumatoid arthritis","volume":"36","author":"Kemp AS","year":"1979","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_19_2","first-page":"131","article-title":"A chemotactic inhibitor in synovial fluid","volume":"49","author":"Matzner Y","year":"1983","journal-title":"Immunology"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780261204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780261204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T21:28:27Z","timestamp":1700688507000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780261204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,12]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1983,12]]}},"alternative-id":["10.1002\/art.1780261204"],"URL":"https:\/\/doi.org\/10.1002\/art.1780261204","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,12]]}}}