{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:34:31Z","timestamp":1756996471288},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":10624,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1977,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A low molecular weight, highly basic DNA\u2010binding protein was purified from several oncornaviruses by the sequential procedures of gel filtration in guanidine\u2010hydrochloride, DEAE\u2010cellulose chromatography and affinity chromatography on single\u2010stranded DNA sepharose. The binding protein from Rauscher and woolly monkey type\u2010C viruses was the fastest migrating of the virion proteins in SDS\u2010polyacrylamide gels and thus is designated p10 according to previous convention although our estimates of molecular weight were 8\u20139,000 daltons. The binding protein from these two viruses was resolved into two bands by acid\u2010urea electrophoresis although only a single NH<jats:sub>2<\/jats:sub> terminal amino acid was detected (S. Oroszlan, personal communication), thus indicating charge heterogeneity. Antibody to Rauscher virus p10 species\u2010specific in gel diffusion and complement\u2010fixation tests and did not exhibit cross\u2010reactivity with other virion proteins. A DNA\u2010binding protein was also detected in preparations of mouse mammary tumor virus. This purified protein had an apparent molecular weight of 12,500, was the second fastest migrating component in the virus preparations, and was antigenically unrelated to the mouse type\u2010C virus p10.<\/jats:p>","DOI":"10.1002\/ijc.2910190616","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T16:53:41Z","timestamp":1171904021000},"page":"843-850","source":"Crossref","is-referenced-by-count":20,"title":["Immunologic studies of the low molecular weight DNA binding protein of murine oncornaviruses"],"prefix":"10.1002","volume":"19","author":[{"given":"Cedric W.","family":"Long","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Berzinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond V.","family":"Gilden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.1016\/S0021-9258(17)33195-2","article-title":"Structural polypeptides of mammalian type C RNA viruses isolation and immunologic characterization of a low molecular weight polypeptide, p10","volume":"251","author":"Barbacid M.","year":"1976","journal-title":"J. biol. Chem."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(73)90057-3"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1128\/jvi.15.6.1378-1384.1975","article-title":"Nucleic acid homology of murine xenotropic type C viruses","volume":"15","author":"Callahan R.","year":"1975","journal-title":"J. Virol."},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1128\/jvi.18.2.709-718.1976","article-title":"Lowmolecular\u2010weight Rauscher leukemia virus protein with preferential binding for single\u2010stranded RNA and DNA","volume":"18","author":"Davis J.","year":"1976","journal-title":"J. Virol."},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1128\/jvi.12.6.1612-1615.1973","article-title":"Isolation of a ribonucleoprotein structure from oncornaviruses","volume":"12","author":"Fleissner E.","year":"1973","journal-title":"J. Virol."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.46123"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(73)90058-5"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1128\/jvi.17.3.727-736.1976","article-title":"Purification and serological characterization of the major envelope glycoprotein from AKR murine leukemia virus and its reactivity with autogenous immune sera from mice","volume":"17","author":"Ihle J. N.","year":"1976","journal-title":"J. Virol."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/260264a0"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-8-1-1"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1128\/jvi.14.6.1559-1574.1974","article-title":"Murine type\u2010C virus group\u2010specific antigens: interstrain immunochemical, biophysical, and amino acid sequence differences","volume":"14","author":"Oroszlan S.","year":"1974","journal-title":"J. Virol."},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1128\/jvi.15.6.1385-1395.1975","article-title":"Serological studies with low\u2010molecular weight polypeptides from the Moloney strain of murine leukemia virus","volume":"15","author":"Parks W. P.","year":"1975","journal-title":"J. Virol."},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1128\/jvi.14.3.430-433.1974","article-title":"Immunological cross\u2010reactions between two lowmolecular\u2010weight polypeptides from a murine type C virus","volume":"14","author":"Parks W. P.","year":"1974","journal-title":"J. Virol."},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00779a011"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(74)90241-4"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1128\/jvi.17.2.374-384.1976","article-title":"Comparisons of the immunological properties of two structural polypeptides of type C RNA viruses endogenous to Old World monkeys","volume":"17","author":"Stephenson J. R.","year":"1976","journal-title":"J. Virol."},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/jvi.15.1.115-120.1975","article-title":"Antigenic characterization of type C RNA virus isolates of Gibbon apes","volume":"15","author":"Tronick S. R.","year":"1975","journal-title":"J. Virol."},{"key":"e_1_2_1_20_1","first-page":"180","volume-title":"The proteins","author":"Weber K.","year":"1975"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910190616","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910190616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T08:17:01Z","timestamp":1699777021000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910190616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,6,15]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1977,6,15]]}},"alternative-id":["10.1002\/ijc.2910190616"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910190616","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,6,15]]}}}