{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T10:30:42Z","timestamp":1773657042721,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T00:00:00Z","timestamp":1153180800000},"content-version":"vor","delay-in-days":8281,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1983,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:sup>32<\/jats:sup>P\u2010labelled DNA of HPV 16 which has been isolated and molecularly cloned from a cervical carcinoma (D\u00fcrst <jats:italic>et al.<\/jats:italic>, 1983) was used to screen the cellular DNAs obtained from 20 different biopsies of Morbus Bowen or Bowenoid papulosis, respectively, by Southern blot analysis. Under conditions of differing stringency for the hybridization, HPV 16 DNA or related sequences were identified in 6 out of 10 cases of Morbus Bowen (4 out of 5 from a genital localization) and in 8 out of 10 biopsies from Bowenoid papulosis. One additional case of the latter disease contained DNA sequences of an HPV type not yet classified. There is evidence for the presence of another HPV DNA in two of the HPV\u201016\u2010positive tumors. A large number of normal genital tissue samples were negative for HPV DNA.<\/jats:p>","DOI":"10.1002\/ijc.2910320507","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T19:28:08Z","timestamp":1171913288000},"page":"563-565","source":"Crossref","is-referenced-by-count":354,"title":["Human papillomavirus type\u201016\u2010related DNA in genital Bowen's disease and in bowenoid papulosis"],"prefix":"10.1002","volume":"32","author":[{"given":"Hans","family":"Ikenberg","sequence":"first","affiliation":[]},{"given":"Lutz","family":"Gissmann","sequence":"additional","affiliation":[]},{"given":"Gerd","family":"Gross","sequence":"additional","affiliation":[]},{"given":"Elke\u2010Ingrid","family":"Grussendorf\u2010Conen","sequence":"additional","affiliation":[]},{"given":"Harald Zur","family":"Hausen","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1001\/archderm.1978.01640230072021","article-title":"Multicentric Bowen's disease of genitalia","volume":"114","author":"Berger B. W.","year":"1978","journal-title":"Arch. Dermat."},{"key":"e_1_2_1_3_1","first-page":"341","article-title":"Erythroplasia of Queyrat","volume":"35","author":"Blau S.","year":"1955","journal-title":"Acta derm. venerol."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.12.3812"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910290205"},{"key":"e_1_2_1_6_1","first-page":"646","volume-title":"Cancer of the skin","author":"Knox J. M.","year":"1976"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000251950"},{"key":"e_1_2_1_8_1","first-page":"288","article-title":"Virus\u2010like particles in Bowen's disease","volume":"30","author":"Nordquist R. E.","year":"1970","journal-title":"Cancer Res."},{"key":"e_1_2_1_9_1","first-page":"2078","article-title":"An electron microscopic study of Bowen's disease","volume":"28","author":"Olson R. L.","year":"1968","journal-title":"Cancer"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197810)42:4<1890::AID-CNCR2820420430>3.0.CO;2-C"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/300771a0"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910320507","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910320507","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T13:52:40Z","timestamp":1697723560000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910320507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,11,15]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1983,11,15]]}},"alternative-id":["10.1002\/ijc.2910320507"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910320507","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,11,15]]}}}