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The measured accumulation of label in nuclear and cytoplasmic poly(A) is examined with the model and parameters were found which are consistent with the quantitative transfer of nuclear poly(A) to the cytoplasm. The strengths and limitations of the model are discussed.<\/jats:p>","DOI":"10.1002\/jcp.1040900315","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T17:31:32Z","timestamp":1109439092000},"page":"521-534","source":"Crossref","is-referenced-by-count":33,"title":["Essential factors in the kinetic analysis of RNA synthesis in HeLa cells"],"prefix":"10.1002","volume":"90","author":[{"given":"Larry","family":"Puckett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James E.","family":"Darnell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-470205-9.50010-1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(75)90102-6"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)96624-5"},{"key":"e_1_2_1_5_1","first-page":"1","article-title":"The origin of nRNA, and the structure of the mammalian chromosome","volume":"69","author":"Darnell J. 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