{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T20:36:28Z","timestamp":1760819788786},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,2]],"date-time":"2005-06-02T00:00:00Z","timestamp":1117670400000},"content-version":"vor","delay-in-days":10867,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Exp. Zool."],"published-print":{"date-parts":[[1975,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dorsal unpaired median (DUM) neurons of locusts and grasshoppers inhibit the instrinsic rhythm of contraction of metathoracic extensor tibia muscle fibers. This physiological action is mimicked by very low concentrations of octopamine and by higher concentrations of dopamine and noradrenaline. We have examined the synthesis of biogenic amines from tritiated tyrosine by these neurons. DUM cell bodies and a peripheral nerve containing the DUM axon which terminates in the extensor tibia both produced octopamine, but neither noradrenaline nor dopamine synthesis was detected. The observations support the suggestion that the dorsal unpaired median neurons are octopaminergic.<\/jats:p>","DOI":"10.1002\/jez.1401930322","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T06:59:38Z","timestamp":1118473178000},"page":"433-439","source":"Crossref","is-referenced-by-count":99,"title":["Synthesis of octopamine by insect dorsal median unpaired neurons"],"prefix":"10.1002","volume":"193","author":[{"given":"Graham","family":"Hoyle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Barker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/newbio236061a0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(75)90317-0"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/10.3.348"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/neu.480020305"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1242\/jeb.30.1.121","article-title":"Potassium ion and insect nerve muscle","volume":"30","author":"Hoyle G.","year":"1953","journal-title":"J. Exp. Biol."},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","unstructured":"Hoyle G.1975Insect dorsal unpaired median (DUM) neurons are octopaminergic.J. Exp. Zool. previous article this issue.","DOI":"10.1002\/jez.1401930321"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1401870119"},{"key":"e_1_2_1_9_1","unstructured":"Hoyle G. andE.FloreyExcitation by acetylcholine and inhibition by catecholamines of the intrinsic rhythm of insect skeletal muscle. In preparation to be submitted toJ. Comp. Physiol."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.180.4083.308"},{"key":"e_1_2_1_11_1","first-page":"34","article-title":"Octopamine in the insect central nervous system: distribution, biosynthesis and possible physiological role","volume":"237","author":"Robertson H. A.","year":"1973","journal-title":"J. Physiol."},{"key":"e_1_2_1_12_1","unstructured":"Sullivan R. E.andD. L.Barker1975Octopamine increases cyclic AMP conte t of crustacean ganglia and cardiac muscle Society for Neuroscience Fifth Annual meeting. Abs. #1056."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)90590-3"}],"container-title":["Journal of Experimental Zoology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjez.1401930322","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jez.1401930322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T12:45:05Z","timestamp":1699793105000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jez.1401930322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,9]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1975,9]]}},"alternative-id":["10.1002\/jez.1401930322"],"URL":"https:\/\/doi.org\/10.1002\/jez.1401930322","archive":["Portico"],"relation":{},"ISSN":["0022-104X","1097-010X"],"issn-type":[{"value":"0022-104X","type":"print"},{"value":"1097-010X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,9]]}}}