{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T21:58:16Z","timestamp":1757541496361},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T00:00:00Z","timestamp":1115856000000},"content-version":"vor","delay-in-days":9538,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Exp. Zool."],"published-print":{"date-parts":[[1979,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The thesis that lymphocytes originate in situ by the direct transformation of epithelial cells within the thymic primordium in anurous frogs is untenable. On the contrary, in both the leopard frog and the African clawed toad, the lymphocytes that first appear in the embryonic thymus are derived from extrathymic lymphopoietc cells that invade the developing organ. The exact source of origin of the invading lymphopoietic cells remains problematic.<\/jats:p>","DOI":"10.1002\/jez.1402080107","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T04:34:43Z","timestamp":1118464483000},"page":"57-66","source":"Crossref","is-referenced-by-count":23,"title":["Clarification of studies on the origin of thymic lymphocytes"],"prefix":"10.1002","volume":"208","author":[{"given":"E. Peter","family":"Volpe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Tompkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Reinschmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091520106"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(61)90051-3"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00330080"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.2307\/3224268"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1401060303"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1401510203"},{"key":"e_1_2_1_8_1","first-page":"607","article-title":"On the origin of haemopoietic stem cells in the avian embryo: An experimental approach","volume":"33","author":"Dieterlen\u2010Lievre F.","year":"1975","journal-title":"J. embryol. exp. Morph."},{"key":"e_1_2_1_9_1","first-page":"857","article-title":"Origin of erythropoietic stem cells in avian development: Shift from the yolk sac to an intraembryonic site","volume":"127","author":"Dieterlen\u2010Lievre F.","year":"1976","journal-title":"Ann. Immunol. (Inst. Pasteur)"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.142.1.17"},{"key":"e_1_2_1_11_1","first-page":"849","article-title":"Ontogeny of the avian thymus and bursa of Fabricius studied in interspecific chimeras","volume":"127","author":"LeDouarin N.","year":"1976","journal-title":"Ann. Immunol. (Inst. Pasteur)"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/208956a0"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.126.4.715"},{"key":"e_1_2_1_14_1","volume-title":"Normal table of Xenopus larvis (Dausin)","author":"Nieuwkoop P. D.","year":"1975"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/1537458"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/ar.1090780202","article-title":"Stages in the normal development of Rana pipiens. I. External form","volume":"78","author":"Shumway W.","year":"1940","journal-title":"Anat. Rec."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(77)90231-7"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1402030207"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0008-8749(76)90136-2"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.182.4115.931"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/icb\/15.1.51"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-305X(77)80034-7"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(63)90042-3"},{"key":"e_1_2_1_24_1","volume-title":"Developmental Immunobiology","author":"Volpe E. P.","year":"1977"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1081275"}],"container-title":["Journal of Experimental Zoology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjez.1402080107","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jez.1402080107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T15:34:12Z","timestamp":1699803252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jez.1402080107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,4]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1979,4]]}},"alternative-id":["10.1002\/jez.1402080107"],"URL":"https:\/\/doi.org\/10.1002\/jez.1402080107","archive":["Portico"],"relation":{},"ISSN":["0022-104X","1097-010X"],"issn-type":[{"value":"0022-104X","type":"print"},{"value":"1097-010X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,4]]}}}