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These can vary from severe fibrosis, frequently intra\u2010abdominal and causing bowel obstruction, to desmoid tumors and fibrosarcomas, both of which can be progressive and life threatening. This aspect of the syndrome is poorly understood, but must be carefully evaluated in selecting treatment for the associated polyposis coli.<\/jats:p>","DOI":"10.1002\/jso.2930040406","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T01:44:05Z","timestamp":1171935845000},"page":"354-362","source":"Crossref","is-referenced-by-count":14,"title":["Gardner's syndrome, colon cancer, and sarcoma"],"prefix":"10.1002","volume":"4","author":[{"given":"Jerome G.","family":"Johnson","sequence":"first","affiliation":[]},{"given":"Enid","family":"Gilbert","sequence":"additional","affiliation":[]},{"given":"Bernard","family":"Zimmermann","sequence":"additional","affiliation":[]},{"given":"Alvin L.","family":"Watne","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02616574"},{"key":"e_1_2_1_3_1","first-page":"167","article-title":"A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum","volume":"3","author":"Gardner E. 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