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The number of iron transferrin receptors on continuous cell lines as well as normal human fibroblasts is down\u2010regulated during the transition from log\u2010phase growth to stationary plateau growth. When normal lymphocytes are transformed by mixed lymphocyte culture or mitogens, they rapidly express a 50\u2010fold increase in the number of transferrin binding sites. This appearance of iron transferrin receptors anticipates nuclear changes during cell activation and subsequent mitosis of normal cells.<\/jats:p>","DOI":"10.1002\/jss.400110415","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T20:07:08Z","timestamp":1117224428000},"page":"579-586","source":"Crossref","is-referenced-by-count":271,"title":["Modulation of cell surface iron transferrin receptors by cellular density and state of activation"],"prefix":"10.1002","volume":"11","author":[{"given":"James W.","family":"Larrick","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Cresswell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,2,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/259132a0"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02627849"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.2.901"},{"key":"e_1_2_1_5_2","first-page":"3823","volume":"38","author":"Allegra JC","year":"1978","journal-title":"Can Res"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.4.1844"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.147.3.923"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(79)90065-5"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1974.tb06638.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/194495a0"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4827(64)81035-1"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.40.2.297"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910170504"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/278364a0"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/210913a0"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(72)90492-2"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(72)90500-9"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.69.9.2604"},{"key":"e_1_2_1_20_2","first-page":"3","volume":"14","author":"Worwood M","year":"1977","journal-title":"Sem Haematol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-8749(78)90152-1"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/267523a0"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107353"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(76)90154-9"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.4.1619"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/274062a0"}],"container-title":["Journal of Supramolecular Structure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjss.400110415","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jss.400110415","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T14:35:43Z","timestamp":1698849343000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jss.400110415"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,1]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1979,1]]}},"alternative-id":["10.1002\/jss.400110415"],"URL":"https:\/\/doi.org\/10.1002\/jss.400110415","archive":["Portico"],"relation":{},"ISSN":["0091-7419","1547-9366"],"issn-type":[{"value":"0091-7419","type":"print"},{"value":"1547-9366","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,1]]}}}