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The formulation of tissue\u2010like, cell\u2010dense inks for biofabrication remains, however, challenging at various levels of the bioprinting process. Promising advances have been made toward this goal, achieving relatively high cell densities that surpass those found in conventional platforms, pushing the current boundaries closer to achieving tissue\u2010like cell densities. On this focus, herein the overarching challenges in the bioprocessing of cell\u2010rich living inks into clinically grade engineered tissues are discussed, as well as the most recent advances in cell\u2010rich living ink formulations and their processing technologies are highlighted. 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