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However, despite extensive demonstrations of TMD\u2010based nanolasers, further reduction of the lasing threshold is hindered by the challenge of simultaneously achieving an ultra\u2010small mode volume and an ultra\u2010high quality (Q) factor in conventional optical cavities. Moreover, the dielectric interfaces of these cavities induce strong dielectric screening and defect\u2010assisted nonradiative exciton recombination, both of which severely suppress exciton emission in monolayer TMDs. Here, we overcome these fundamental limitations by employing the air modes in a twisted lattice nanocavity. By twisting two finite\u2010sized hexagonal photonic crystal structures in a single layer of SiN\n                    <jats:italic>\n                      <jats:sub>x<\/jats:sub>\n                    <\/jats:italic>\n                    thin film, we introduce a radial, quasi\u2010continuous gradient in the air\u2010filling fraction, thereby forming a radially graded bandgap. This graded bandgap acts as concentric mirrors that tightly confine Bloch modes at the\n                    <jats:italic>K<\/jats:italic>\n                    \u2010point, yielding air modes with extreme field confinement in the air and ultra\u2010high Q factors. By integrating a monolayer WS\n                    <jats:sub>2<\/jats:sub>\n                    with the twisted lattice SiN\n                    <jats:italic>\n                      <jats:sub>x<\/jats:sub>\n                    <\/jats:italic>\n                    nanocavity, we experimentally achieve a record\u2010low lasing threshold of 0.03\u00a0W\/cm\n                    <jats:sup>2<\/jats:sup>\n                    at room temperature. Our work establishes a versatile platform for advanced two\u2010dimensional (2D) semiconductor light sources.\n                  <\/jats:p>","DOI":"10.1002\/adma.74287","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T13:55:43Z","timestamp":1784728543000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Twist Engineering of Photonic Crystal Cavities for Ultralow\u2010Threshold Continuous\u2010Wave WS\n                    <sub>2<\/sub>\n                    Nanolasers at Room Temperature"],"prefix":"10.1002","author":[{"given":"Yuhua","family":"Chen","sequence":"first","affiliation":[{"name":"Suzhou Institute of Nano\u2010Tech and Nano\u2010Bionics (SINANO) Chinese Academy of Sciences (CAS)  Suzhou Jiangsu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Xia","sequence":"additional","affiliation":[{"name":"Suzhou Institute of Nano\u2010Tech and Nano\u2010Bionics (SINANO) Chinese Academy of Sciences (CAS)  Suzhou Jiangsu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9378-0947","authenticated-orcid":false,"given":"Kai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Suzhou Institute of Nano\u2010Tech and Nano\u2010Bionics (SINANO) Chinese Academy of Sciences (CAS)  Suzhou Jiangsu People's Republic of China"},{"name":"School of Nano\u2010Tech and Nano\u2010Bionics University of Science and Technology of China  Hefei Anhui People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingwang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Suzhou Institute of Nano\u2010Tech and Nano\u2010Bionics (SINANO) Chinese Academy of Sciences (CAS)  Suzhou Jiangsu People's Republic of China"},{"name":"School of Nano\u2010Tech and Nano\u2010Bionics University of Science and Technology of China  Hefei Anhui People's Republic of 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