{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:58:11Z","timestamp":1772117891303,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Synth Catal"],"published-print":{"date-parts":[[2020,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The Murai reaction is a ruthenium\u2010catalyzed transformation leading to alkylated arenes through the C\u2212C bond formation between an alkene and an arene bearing a directing group. Discovered in the nineties, this useful C\u2212H activation based coupling has been the object of intense study since its discovery. After having studied the Murai reaction on 2\u2010formylfurans of biomass derivation, we describe here the carbonylative version applied to 2\u2010formylfurans, 2\u2010formylpyrrols and 2\u2010formylthiophenes. This acylation reaction takes place regioselectively at C3 position of the heterocyclopentadienes thanks to the installation of removable imine directing groups. The transformation can be achieved by treating the two reaction partners with a catalytic amount of Ru\n                    <jats:sub>3<\/jats:sub>\n                    (CO)\n                    <jats:sub>12<\/jats:sub>\n                    , in toluene at 120\u2013150\u2009\u00b0C, after CO bubbling, at atmospheric pressure. DFT computations of the full catalytic cycle help in deciphering the mechanism of this transformation, and to rationalize the different behaviors depending on the nature of imine directing groups.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                      <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/adsc202000249-toc-0001-m.png\">\n                        <jats:alt-text>magnified image<\/jats:alt-text>\n                      <\/jats:graphic>\n                    <\/jats:boxed-text>\n                  <\/jats:p>","DOI":"10.1002\/adsc.202000249","type":"journal-article","created":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T22:12:37Z","timestamp":1587075157000},"page":"2486-2493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Ru\u2010Catalyzed Carbonylative Murai Reaction: Directed C3\u2010Acylation of Biomass\u2010Derived 2\u2010Formyl Heteroaromatics"],"prefix":"10.1002","volume":"362","author":[{"given":"Roberto","family":"Sala","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9, Facult\u00e9 des Sciences et Ing\u00e9nierie, CNRS Institut Parisien de Chimie Mol\u00e9culaire, IPCM  4 place Jussieu 75005 Paris France"},{"name":"Dipartimento di Scienza e Alta Tecnologia (DISAT) Universit\u00e0 degli Studi dell'Insubria  Via Valleggio 9 Como (CO) Italy"}]},{"given":"Fares","family":"Roudesly","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Facult\u00e9 des Sciences et Ing\u00e9nierie, CNRS Institut Parisien de Chimie Mol\u00e9culaire, IPCM  4 place Jussieu 75005 Paris France"}]},{"given":"Luis F.","family":"Veiros","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural and Departamento de Engenharia Qu\u00edmica, Instituto Superior T\u00e9cnico Universidade de Lisboa  Av Rovisco Pais 1049-001 Lisboa Portugal"}]},{"given":"Gianluigi","family":"Broggini","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienza e Alta Tecnologia (DISAT) Universit\u00e0 degli Studi dell'Insubria  Via Valleggio 9 Como (CO) Italy"}]},{"given":"Julie","family":"Oble","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Facult\u00e9 des Sciences et Ing\u00e9nierie, CNRS Institut Parisien de Chimie Mol\u00e9culaire, IPCM  4 place Jussieu 75005 Paris France"}]},{"given":"Giovanni","family":"Poli","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Facult\u00e9 des Sciences et Ing\u00e9nierie, CNRS Institut Parisien de Chimie Mol\u00e9culaire, IPCM  4 place Jussieu 75005 Paris France"}]}],"member":"311","published-online":{"date-parts":[[2020,4,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/b922014c"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cssc.201600507"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00395"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-018-0005-y"},{"key":"e_1_2_6_6_1","first-page":"731","volume":"1","author":"Resasco D. 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