{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T12:34:02Z","timestamp":1772800442125,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,2,6]],"date-time":"2015-02-06T00:00:00Z","timestamp":1423180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Funda\u00c3\u00a7\u00c3\u00a3o para a Ci\u00c3\u00aancia e Tecnologia","award":["SFRH\/BD\/86941\/2012"],"award-info":[{"award-number":["SFRH\/BD\/86941\/2012"]}]},{"name":"Funda\u00c3\u00a7\u00c3\u00a3o para a Ci\u00c3\u00aancia e Tecnologia","award":["PEst-C\/EQB\/UI0511"],"award-info":[{"award-number":["PEst-C\/EQB\/UI0511"]}]},{"name":"Programa Operacional do Norte","award":["ON2"],"award-info":[{"award-number":["ON2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Adv Polym Technol"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A molecularly imprinted polymer (MIP) for melamine was prepared by suspension polymerization, using melamine as a template, methacrylic acid as a functional monomer, and ethylene glycol dimethacrylate as a cross\u2010linker. The optimal template\/monomer and monomer\/cross\u2010linker ratios were obtained, being defined as 1\/15 and 1\/12, respectively. Molecular recognition properties and binding capacity toward melamine were evaluated by adsorption tests. Compared with the nonimprinted polymer, the\u00a0imprinted polymer showed higher affinity for melamine with a dissociation constant (<jats:italic>K<jats:sub>d<\/jats:sub><\/jats:italic>) and a maximum binding concentration of 568.4 \u00b1 7.4 \u03bcmol\/L and 96.8\u00a0\u00b1\u00a02.3 \u03bcmol\/g, respectively. Under optimal conditions, the imprinted polymer was used as a dispersive extraction sorbent to extract melamine from different milk samples, before high performance liquid chromatography with diode array detection (HPLC\u2010DAD) analysis. The validated method presented a limit of detection of 0.6 mg\/kg. From the analysis of six different milks, melamine was detected in two of the considered samples at a maximum concentration of 9.3 \u00b1 0.3 mg\/kg.<\/jats:p>","DOI":"10.1002\/adv.21506","type":"journal-article","created":{"date-parts":[[2015,2,6]],"date-time":"2015-02-06T11:58:52Z","timestamp":1423223932000},"source":"Crossref","is-referenced-by-count":12,"title":["Synthesis of a Molecularly Imprinted Polymer for Melamine Analysis in Milk by HPLC with Diode Array Detection"],"prefix":"10.1002","volume":"34","author":[{"given":"Leandro","family":"Figueiredo","sequence":"first","affiliation":[{"name":"LEPABE \u2013 Laboratory for Process Engineering, Environment Biotechnology and Energy Faculdade de Engenharia da Universidade do Porto  4200\u2013465 Porto Portugal"}]},{"given":"L\u00facia","family":"Santos","sequence":"additional","affiliation":[{"name":"LEPABE \u2013 Laboratory for Process Engineering, Environment Biotechnology and Energy Faculdade de Engenharia da Universidade do Porto  4200\u2013465 Porto Portugal"}]},{"given":"Arminda","family":"Alves","sequence":"additional","affiliation":[{"name":"LEPABE \u2013 Laboratory for Process Engineering, Environment Biotechnology and Energy Faculdade de Engenharia da Universidade do Porto  4200\u2013465 Porto Portugal"}]}],"member":"311","published-online":{"date-parts":[[2015,2,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00032719.2011.649458"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2009.12.079"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200900815"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2010.03.037"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2010.06.011"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201200784"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(01)87213-0"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-7799(89)90006-1"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/i7050155"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2008.05.057"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1365\/s10337-006-0097-2"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-5794-0"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac070644q"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201100046"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-008-2454-5"},{"key":"e_1_2_5_17_1","first-page":"1","author":"Zhang H.","year":"2012","journal-title":"Food Anal Methods"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2012.07.037"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201100612"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00604-011-0613-4"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2010.07.003"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201200096"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2009.06.081"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2012.09.022"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2009.07.067"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms12074327"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2005.07.012"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826070600574739"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-9936(97)00037-X"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2006.10.068"},{"key":"e_1_2_5_31_1","unstructured":"E. 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