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Synthesised by a chloride anion templation strategy, the [3]rotaxane host recognises dicarboxylates through the formation of 1:1 stoichiometric sandwich complexes. This process was analysed by molecular dynamics simulations, which revealed the critical synergy of halogen and hydrogen bonding interactions in anion discrimination. In addition, the centrally located chiral (<jats:italic>S<\/jats:italic>)\u2010BINOL motif of the [3]rotaxane axle component facilitates the complexed dicarboxylate species to be sensed via a fluorescence response.<\/jats:p>","DOI":"10.1002\/ange.201711176","type":"journal-article","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T12:13:31Z","timestamp":1511784811000},"page":"593-597","source":"Crossref","is-referenced-by-count":35,"title":["A Chiral Halogen\u2010Bonding [3]Rotaxane for the Recognition and Sensing of Biologically Relevant Dicarboxylate Anions"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8020-1720","authenticated-orcid":false,"given":"Jason Y. 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