{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T03:25:58Z","timestamp":1773458758641,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,1,26]],"date-time":"2005-01-26T00:00:00Z","timestamp":1106697600000},"content-version":"vor","delay-in-days":3619,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1995,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: A peculiar feature of lung circulation in the lung is the pronounced variations in blood volume observed in alveolar capillaries that occur because of the changes in the conformation of the alveolar wall that are associated with the respiratory movements. This phenomenon has led to the postulate that mechanisms of postcapillary control of blood flow are to be present in the lung vessels. In the present study we searched for microanatomical evidence of vascular sphincters in the deep lung tissue of mice, namely in alveolar capillaries and pulmonary veins.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: We have used scanning electron microscopy (SEM) to examine two types of samples of normal lung tissue of CD\u20101 mice: 1) vascular corrosion casts made by vascular perfusion with Mercox\u00ae resin, and 2) routinely made gold\/platinum\u2010coated replicas of sectioned lung tissue.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: Careful scrutiny of the vessels of the deep lung tissue led to the identification of sphincters in alveolar capillaries. These sphincters were located at the junction between capillary and pulmonary veins. They corresponded to areas to the vascular wall showing circular swellings where a radial organization was observed, since they were made up of alternating grooves and bulges. Transmission electron microscopy showed that smooth muscle cells participated in the formation of the sphincters.<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>: Our data reveal a new location for vascular sphincters in pulmonary vessels and, because these novel sphincters are located at the capillary\u2010vein junction, they offer a structural setting for the existence of postcapillary control of blood flow in the pulmonary circulation of mice. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.1092410313","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T19:11:47Z","timestamp":1109445107000},"page":"383-390","source":"Crossref","is-referenced-by-count":6,"title":["Identification of vascular sphincters at the junction between alveolar capillaries and pulmonary venules of the mouse lung"],"prefix":"10.1002","volume":"241","author":[{"given":"M\u00e1rio N. D.","family":"Pe\u00e1to","sequence":"first","affiliation":[]},{"given":"Artur P.","family":"\u00c1guas","sequence":"additional","affiliation":[]},{"given":"Carlos M.","family":"De S\u00c1","sequence":"additional","affiliation":[]},{"given":"Nuno Rodrigues","family":"Grande","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/10520298209066530"},{"key":"e_1_2_1_3_1","first-page":"1091","article-title":"Sphincters in the rat pulmonary veins. Comparison of scanning electron and transmission electron microscopic studies","volume":"5","author":"Aharinejad S.","year":"1991","journal-title":"Scanning Microsc."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092330410"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/sca.4950120507"},{"key":"e_1_2_1_6_1","first-page":"767","volume-title":"The Lung: Scientific Foundations","author":"de Mello D.","year":"1991"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.3.2.152"},{"key":"e_1_2_1_8_1","unstructured":"Grande N. R.1965Pulmonary Arterial Hypertension. Ph.D. thesis University of Porto Porto Portugal."},{"key":"e_1_2_1_9_1","first-page":"129","article-title":"El factor obstructivo en la hypertension arterial pulmonar","author":"Grande N. R.","year":"1970","journal-title":"Rev. Med. Univ. Navarra"},{"key":"e_1_2_1_10_1","volume-title":"Histology","author":"Ham A. 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