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This work aimed to explore the anti\u2010inflammatory potential of aqueous extracts from two herbal teas (<jats:italic>Annona muricata<\/jats:italic>L. and<jats:italic>Jasminum grandiflorum<\/jats:italic>L.) in<jats:styled-content style=\"fixed-case\">RAW<\/jats:styled-content>264.7 macrophages cells and in cell\u2010free assays. Furthermore, the phenolic composition of both extracts and of their hydrolysates was characterized by<jats:styled-content style=\"fixed-case\">HPLC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">DAD<\/jats:styled-content>, in order to establish possible relationships with the biological activity. In a general way,<jats:italic>A.\u00a0muricata<\/jats:italic>displayed a stronger capacity to inhibit nitric oxide (<jats:styled-content style=\"fixed-case\">NO<\/jats:styled-content>) production and the activity of phospholipase A<jats:sub>2<\/jats:sub>(<jats:styled-content style=\"fixed-case\">PLA<\/jats:styled-content><jats:sub>2<\/jats:sub>), displaying an<jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub>value of 142\u00a0\u03bcg\/ml against this enzyme. A deeper look at phenolic compounds revealed that aglycones had more capacity to inhibit<jats:styled-content style=\"fixed-case\">NO<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">PLA<\/jats:styled-content><jats:sub>2<\/jats:sub>than their corresponding glycosides, quercetin being clearly the most potent one (<jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub>\u00a0=\u00a07.47 and 1.36\u00a0\u03bc<jats:sc>m<\/jats:sc>, respectively). In addition, 5\u2010<jats:italic>O<\/jats:italic>\u2010caffeoylquinic acid, at 1.56\u00a0\u03bc<jats:sc>m<\/jats:sc>, could also inhibit<jats:styled-content style=\"fixed-case\">PLA<\/jats:styled-content><jats:sub>2<\/jats:sub>(<jats:italic>ca<\/jats:italic>. 35%). Our findings suggest that the consumption of both herbal teas may be a preventive approach to inflammatory disorders.<\/jats:p>","DOI":"10.1002\/cbdv.201700002","type":"journal-article","created":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T01:42:46Z","timestamp":1488505366000},"source":"Crossref","is-referenced-by-count":12,"title":["Exploratory Studies on the<i>in Vitro<\/i>Anti\u2010inflammatory Potential of Two Herbal Teas (<i>Annona muricata<\/i>L. and<i>Jasminum grandiflorum<\/i>L.), and Relation with Their Phenolic Composition"],"prefix":"10.1002","volume":"14","author":[{"given":"Andreia P.","family":"Oliveira","sequence":"first","affiliation":[{"name":"REQUIMTE\/LAQV Laborat\u00f3rio de Farmacognosia Departamento de Qu\u00edmica Faculdade de Farm\u00e1cia Universidade do Porto R. Jorge Viterbo Ferreira, no. 228 PT\u20104050\u2010313 Porto"}]},{"given":"Ivone","family":"S\u00e1","sequence":"additional","affiliation":[{"name":"REQUIMTE\/LAQV Laborat\u00f3rio de Farmacognosia Departamento de Qu\u00edmica Faculdade de Farm\u00e1cia Universidade do Porto R. Jorge Viterbo Ferreira, no. 228 PT\u20104050\u2010313 Porto"}]},{"given":"David M.","family":"Pereira","sequence":"additional","affiliation":[{"name":"REQUIMTE\/LAQV Laborat\u00f3rio de Farmacognosia Departamento de Qu\u00edmica Faculdade de Farm\u00e1cia Universidade do Porto R. Jorge Viterbo Ferreira, no. 228 PT\u20104050\u2010313 Porto"}]},{"given":"Rui F.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"REQUIMTE\/LAQV Laborat\u00f3rio de Farmacognosia Departamento de Qu\u00edmica Faculdade de Farm\u00e1cia Universidade do Porto R. Jorge Viterbo Ferreira, no. 228 PT\u20104050\u2010313 Porto"}]},{"given":"Paula B.","family":"Andrade","sequence":"additional","affiliation":[{"name":"REQUIMTE\/LAQV Laborat\u00f3rio de Farmacognosia Departamento de Qu\u00edmica Faculdade de Farm\u00e1cia Universidade do Porto R. Jorge Viterbo Ferreira, no. 228 PT\u20104050\u2010313 Porto"}]},{"given":"Patr\u00edcia","family":"Valent\u00e3o","sequence":"additional","affiliation":[{"name":"REQUIMTE\/LAQV Laborat\u00f3rio de Farmacognosia Departamento de Qu\u00edmica Faculdade de Farm\u00e1cia Universidade do Porto R. 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