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Emb.) R. Morales, two Lamiaceae endemic to south Morocco, were investigated. GC\/MS analysis resulted in the identification of 36 metabolites from the EO of <jats:italic>M.\u2005macrosiphon<\/jats:italic>, 45 from <jats:italic>M.\u2005arganietorum<\/jats:italic>. Borneol was the major metabolite in both oils and together with related derivatives such as camphor, accounted for 2\/3 of the EO of <jats:italic>M.\u2005macrosiphon<\/jats:italic>, 1\/3 of those of <jats:italic>M.\u2005arganietorum<\/jats:italic>. Pinene and terpinene derivatives were also present in high proportions. From a chemotaxonomic point of view, the composition of the examined samples may be related to those of other species endemic to Macaronesia. Both EOs showed significant toxicity towards liver HepG2 and melanoma B16 4A5 tumor cell lines at 100\u2005\u03bcg\/mL; however, they were also cytotoxic towards S17 normal cell lines, with a selectivity index &lt;1. No antibacterial activity was noticed against 52 strains at 100\u2005\u03bcg\/mL.<\/jats:p>","DOI":"10.1002\/cbdv.202100653","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T04:25:18Z","timestamp":1637123118000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chemical Composition and Biological Screening of the Essential Oils of <i>Micromeria macrosiphon<\/i> and <i>M. arganietorum<\/i> (Lamiaceae)"],"prefix":"10.1002","volume":"18","author":[{"given":"Mohamed","family":"El Yaagoubi","sequence":"first","affiliation":[{"name":"Laboratory of Biotechnologies and Valorization of Natural Resources Faculty of Sciences University Ibn Zhor  80060 Agadir Morocco"}]},{"given":"Hicham","family":"Mechqoq","sequence":"additional","affiliation":[{"name":"Laboratory of Biotechnologies and Valorization of Natural Resources Faculty of Sciences University Ibn Zhor  80060 Agadir Morocco"}]},{"given":"Sergio","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Natural products, Analysis, Synthesis, UMR CNRS 8038 CiTCoM Faculty of Pharmacy University of Paris  75006 Paris France"}]},{"given":"Carlos","family":"Cavaleiro","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy of the University of Coimbra University of Coimbra Health Sciences Campus, Azinhaga de S. Comba  3000-548 Coimbra Portugal"},{"name":"Chemical Process Engineering and Forest Products Research Center Universidade de Coimbra  Rua S\u00edlvio Lima, Polo\u2005II 3030-790 Coimbra Portugal"}]},{"given":"Marylin","family":"Lecs\u00f6\u2010Bornet","sequence":"additional","affiliation":[{"name":"Natural products, Analysis, Synthesis, UMR CNRS 8038 CiTCoM Faculty of Pharmacy University of Paris  75006 Paris France"}]},{"given":"Catarina Guerreiro","family":"Pereira","sequence":"additional","affiliation":[{"name":"Center of Marine Sciences Faculty of Sciences and Technology University of Algarve, Ed.\u20057 Campus of Gambelas  8005-139 Faro Portugal"}]},{"given":"Maria Jo\u00e3o","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Center of Marine Sciences Faculty of Sciences and Technology University of Algarve, Ed.\u20057 Campus of Gambelas  8005-139 Faro Portugal"}]},{"given":"Lu\u00edsa","family":"Cust\u00f3dio","sequence":"additional","affiliation":[{"name":"Center of Marine Sciences Faculty of Sciences and Technology University of Algarve, Ed.\u20057 Campus of Gambelas  8005-139 Faro Portugal"}]},{"given":"Abdelhamid","family":"El Mousadik","sequence":"additional","affiliation":[{"name":"Laboratory of Biotechnologies and Valorization of Natural Resources Faculty of Sciences University Ibn Zhor  80060 Agadir Morocco"}]},{"given":"Laurent","family":"Picot","sequence":"additional","affiliation":[{"name":"La Rochelle Universit\u00e9 UMRi CNRS 7266 Littoral Environnement et Soci\u00e9t\u00e9s LIENSs  17042 La Rochelle France"}]},{"given":"Marina","family":"Kritsanida","sequence":"additional","affiliation":[{"name":"Natural products, Analysis, Synthesis, UMR CNRS 8038 CiTCoM Faculty of Pharmacy University of Paris  75006 Paris France"}]},{"given":"Fouad","family":"Msanda","sequence":"additional","affiliation":[{"name":"Laboratory of Biotechnologies and Valorization of Natural Resources Faculty of Sciences University Ibn Zhor  80060 Agadir Morocco"}]},{"given":"Noureddine","family":"El Aouad","sequence":"additional","affiliation":[{"name":"Laboratory of Biotechnologies and Valorization of Natural Resources Faculty of Sciences University Ibn Zhor  80060 Agadir Morocco"},{"name":"Research Team on Biological Engerineering, Agrifood and Aquaculture Polydisciplinary Faculty of Larache. 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