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The subsp. <jats:italic>greuteri<\/jats:italic> and <jats:italic>carbonellii<\/jats:italic> showed higher extract yields. Terpenoids were the most abundant chemical class in subsp. <jats:italic>carbonellii<\/jats:italic>, <jats:italic>greuteri<\/jats:italic>, <jats:italic>trialata<\/jats:italic>, and <jats:italic>vejerensis<\/jats:italic>, while alkanes were the most abundant in subsp. <jats:italic>marginata<\/jats:italic>. Differences in chemical constituents were identified among the subspecies of <jats:italic>C. suffruticosa<\/jats:italic> analysed, which the PCA can prove. The subsp. <jats:italic>trialata<\/jats:italic> and <jats:italic>greuteri<\/jats:italic> showed more significant phytochemical similarity, which might indicate genetic proximity between these two subspecies. <jats:italic>C. suffruticosa<\/jats:italic> subsp. <jats:italic>marginata<\/jats:italic> presented the fewest number of compounds and in the smallest quantities, and <jats:italic>C. suffruticosa<\/jats:italic> subsp. <jats:italic>vejerensis<\/jats:italic> presented the largest number, however, both showed no alcohols. Furthermore, some of the compounds found in significant amounts are known for their pharmacological and nutraceutical properties, denoting potential use.<\/jats:p>","DOI":"10.1002\/cbdv.202200367","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T02:23:35Z","timestamp":1666578215000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chemical Variability of Hexane Extracts from Five Subspecies of <i>Calendula suffruticosa<\/i> from Spain"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7168-7124","authenticated-orcid":false,"given":"Silvana","family":"Ohse","sequence":"first","affiliation":[{"name":"Department of Phytotechnics and Fitossanity State University of Ponta Grossa, Campus Uvaranas  General Carlos Cavalcanti Avenue-4748 84030-900 Ponta Grossa-Paran\u00e1 Brazil"},{"name":"CESAM-Center for Environmental and Marine Studies Department of Biology University of Aveiro  3810-193 Aveiro Portugal"},{"name":"LAQV-REQUIMTE &amp; Department of Chemistry University of Aveiro  Campus de Santiago 3810-193 Aveiro Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6225-5258","authenticated-orcid":false,"given":"Mariza B.","family":"Marques","sequence":"additional","affiliation":[{"name":"Department of Chemistry State University of Ponta Grossa  84030-900 Ponta Grossa-Paran\u00e1 Brazil"},{"name":"CESAM-Center for Environmental and Marine Studies Department of Biology University of Aveiro  3810-193 Aveiro Portugal"},{"name":"LAQV-REQUIMTE &amp; Department of Chemistry University of Aveiro  Campus de Santiago 3810-193 Aveiro Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9253-5381","authenticated-orcid":false,"given":"Paulo C.","family":"Silveira","sequence":"additional","affiliation":[{"name":"CESAM-Center for Environmental and Marine Studies Department of Biology University of Aveiro  3810-193 Aveiro Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8261-8175","authenticated-orcid":false,"given":"M\u00f3nica S. 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