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Herein, we present the synthesis and the characterization of a nanostructured well\u2010defined core\u2013shell nanogel with the ability to stabilize Pd<jats:sup>0<\/jats:sup> nanoparticles in its core. This hybrid nanogel displays a remarkable stability in both the solid state and in solution. This feature allowed its successful application as a catalyst for the Mizoroki\u2013Heck reaction between <jats:italic>n<\/jats:italic>\u2010butyl acrylate and a series of bromo\u2010 and iodoarenes. The yields spanned from good to excellent, and catalyst recycling could be achieved up to three times without a significant activity loss. Three\u2010phase tests indicated that the hybrid nanogel acts as a Pd<jats:sup>0<\/jats:sup> nanoreservoir. The catalysis proceeds in a quasihomogeneous fashion as part of the catalytic activity occurs outside the nanogel, which explains the observed limited recyclability.<\/jats:p>","DOI":"10.1002\/cctc.201601645","type":"journal-article","created":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T06:16:49Z","timestamp":1488521809000},"page":"2167-2175","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Palladium(0) Nanoparticles Embedded in Core\u2013shell Nanogels as Recoverable Catalysts for the Mizoroki\u2013Heck Reaction"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5269-6861","authenticated-orcid":false,"given":"Andr\u00e9","family":"Pontes\u2005da\u2005Costa","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, CNRS Institut Parisien de Chimie Mol\u00e9culaire (IPCM), UMR 8232  4 place Jussieu 75005 Paris France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-2869","authenticated-orcid":false,"given":"Danilo Rosa","family":"Nunes","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, CNRS Institut Parisien de Chimie Mol\u00e9culaire (IPCM), UMR 8232  4 place Jussieu 75005 Paris France"},{"name":"The Research Institute for Medicines (iMed. ULisboa), Faculty of Pharmacy University of Lisbon  Av. Prof. Gama Pinto 1649-003 Lisboa Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6131-655X","authenticated-orcid":false,"given":"Micka\u00ebl","family":"Tharaud","sequence":"additional","affiliation":[{"name":"Institut de Physique du Globe de Paris (IPGP), Sorbonne Paris Cit\u00e9, Univ Paris Diderot, UMR 7154 CNRS  1 rue Jussieu 75005 Paris France"}]},{"given":"Julie","family":"Oble","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, CNRS Institut Parisien de Chimie Mol\u00e9culaire (IPCM), UMR 8232  4 place Jussieu 75005 Paris France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7356-1568","authenticated-orcid":false,"given":"Giovanni","family":"Poli","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, CNRS Institut Parisien de Chimie Mol\u00e9culaire (IPCM), UMR 8232  4 place Jussieu 75005 Paris France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9391-4917","authenticated-orcid":false,"given":"Jutta","family":"Rieger","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, UPMC Univ Paris 06, CNRS Institut Parisien de Chimie Mol\u00e9culaire (IPCM), UMR 8232  4 place Jussieu 75005 Paris France"}]}],"member":"311","published-online":{"date-parts":[[2017,5,18]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"\u00a0"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1039\/b406719n"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic062183h"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejic.200800569"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar400168s"},{"key":"e_1_2_7_6_1","unstructured":"\u00a0"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1039\/C39840001287"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4020(96)00547-9"},{"key":"e_1_2_7_9_1","unstructured":"\u00a0"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(98)01967-4"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol035184b"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2006.12.024"},{"key":"e_1_2_7_13_1","unstructured":"\u00a0"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1039\/b506784g"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1039\/B604544H"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6NJ02279K"},{"key":"e_1_2_7_17_1","unstructured":"\u00a0"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1595\/147106712X632415"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11244-013-0082-6"},{"key":"e_1_2_7_20_1","unstructured":"\u00a0"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/b96865"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr8004235"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/mz500075b"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2016.03.002"},{"key":"e_1_2_7_25_1","unstructured":"\u00a0"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1381-1169(00)00436-2"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200304977"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/la0350709"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1039\/b413885f"},{"key":"e_1_2_7_30_1","first-page":"113","volume":"140","author":"Lu Y.","year":"2013","journal-title":"Prog. 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