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All synthesized compounds have shown a colorimetric response and fluorescence ON\u2013OFF behavior to the presence of lead, calcium, magnesium, and copper, with higher affinity toward the latter, even in the presence of other cations in solution. Optical spectroscopies, X\u2010ray crystallography, and EPR experiments show that Cu(II) induces an irreversible oxidation on the coumarin core, with the concomitant formation of Cu(I) and an organic radical species. The emergence of an absorption band in the visible region upon radical formation results in the appearance of blue color, which fades over time, highlighting the potential of these sensors for rapid detection of copper(II) ion under the naked eye.<\/jats:p>","DOI":"10.1002\/ceur.202500431","type":"journal-article","created":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T14:10:53Z","timestamp":1771769453000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Coumarin\u20103\u2010Carboxamide Derivatives as Colorimetric\/Fluorescent Chemosensors for the Detection of Ca\n                    <sup>2+<\/sup>\n                    , Mg\n                    <sup>2+<\/sup>\n                    , Pb\n                    <sup>2+<\/sup>\n                    , and Selective Recognition of Cu\n                    <sup>2+<\/sup>"],"prefix":"10.1002","volume":"4","author":[{"given":"Liliana J.","family":"Gomes","sequence":"first","affiliation":[{"name":"LAQV REQUIMTE Chemistry Department NOVA School of Science and Technology | NOVA FCT  Caparica Portugal"}]},{"given":"Lu\u00edsa","family":"Maia","sequence":"additional","affiliation":[{"name":"LAQV REQUIMTE Chemistry Department NOVA School of Science and Technology | NOVA FCT  Caparica Portugal"}]},{"given":"Mani","family":"Outis","sequence":"additional","affiliation":[{"name":"LAQV REQUIMTE Chemistry Department NOVA School of Science and Technology | NOVA FCT  Caparica Portugal"},{"name":"Centro de Qu\u00edmica Estrutural Institute of Molecular Sciences Instituto Superior T\u00e9cnico Universidade de Lisboa  Lisboa Portugal"}]},{"given":"Clara S. 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