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The stability constant values of the divalent and trivalent metal\u2010ion complexes are between the corresponding values of H<jats:sub>4<\/jats:sub>dota and H<jats:sub>8<\/jats:sub>dotp complexes, as a consequence of the ligand basicity. The solid\u2010state structures of the ligand and of nine lanthanide(III) complexes were determined by X\u2010ray diffraction. All the complexes are present as twisted\u2010square\u2010antiprismatic isomers and their structures can be divided into two series. The first one involves nona\u2010coordinated complexes of the large lanthanide(III) ions (Ce, Nd, Sm) with a coordinated water molecule. In the series of Sm, Eu, Tb, Dy, Er, Yb, the complexes are octa\u2010coordinated only by the ligand donor atoms and their coordination cages are more irregular. The formation kinetics and the acid\u2010assisted dissociation of several Ln<jats:sup>III<\/jats:sup>\u2013H<jats:sub>6<\/jats:sub><jats:bold>L<\/jats:bold> complexes were investigated at different temperatures and compared with analogous data for complexes of other dota\u2010like ligands. The [Ce(<jats:bold>L<\/jats:bold>)(H<jats:sub>2<\/jats:sub>O)]<jats:sup>3\u2212<\/jats:sup> complex is the most kinetically inert among complexes of the investigated lanthanide(III) ions (Ce, Eu, Gd, Yb). Among mixed phosphonate\u2013acetate dota analogues, kinetic inertness of the cerium(III) complexes is increased with a higher number of phosphonate arms in the ligand, whereas the opposite is true for europium(III) complexes. According to the <jats:sup>1<\/jats:sup>H\u2005NMR spectroscopic pseudo\u2010contact shifts for the Ce\u2013Eu and Tb\u2013Yb series, the solution structures of the complexes reflect the structures of the [Ce(H<jats:bold>L<\/jats:bold>)(H<jats:sub>2<\/jats:sub>O)]<jats:sup>2\u2212<\/jats:sup> and [Yb(H<jats:bold>L<\/jats:bold>)]<jats:sup>2\u2212<\/jats:sup> anions, respectively, found in the solid state. However, these solution NMR spectroscopic studies showed that there is no unambiguous relation between <jats:sup>31<\/jats:sup>P\/<jats:sup>1<\/jats:sup>H lanthanide\u2010induced shift (LIS) values and coordination of water in the complexes; the values rather express a relative position of the central ions between the N<jats:sub>4<\/jats:sub> and O<jats:sub>4<\/jats:sub> planes.<\/jats:p>","DOI":"10.1002\/chem.201000320","type":"journal-article","created":{"date-parts":[[2010,6,10]],"date-time":"2010-06-10T02:37:59Z","timestamp":1276137479000},"page":"8446-8465","source":"Crossref","is-referenced-by-count":45,"title":["Lanthanide(III) Complexes of 4,10\u2010Bis(phosphonomethyl)\u20101,4,7,10\u2010tetraazacyclododecane\u20101,7\u2010diacetic acid (<i>trans<\/i>\u2010H<sub>6<\/sub>do2a2p) in Solution and in the Solid State: Structural Studies Along the Series"],"prefix":"10.1002","volume":"16","author":[{"given":"M. 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