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To date, these endeavors have been supported by developments in SERS substrate nanofabrication, instrumentation portability, and the internet of things. Here, we report distinct chemical strategies for preparing magneto\u2010plasmonic (Fe<jats:sub>3<\/jats:sub>O<jats:sub>4<\/jats:sub>\u2009:\u2009Au) colloids, which are relevant in the context of trace\u2010level detection of water contaminants due to their inherent multifunctionality. The main objective of this research is to investigate the role of poly(amidoamine) dendrimers (PAMAMs) in the preparation of SERS substrates integrating both functionalities into single nanostructures. Three chemical routes were investigated to design magneto\u2010plasmonic nanostructures that translate into different ways for assessing SERS detection by using distinct interfaces. Hence, a series of magneto\u2010plasmonic colloids have been characterized and then assessed for their SERS activity by using a model pesticide (thiram) dissolved in aqueous samples.<\/jats:p>","DOI":"10.1002\/chem.202202382","type":"journal-article","created":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T16:49:43Z","timestamp":1662742183000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Chemical Strategies for Dendritic Magneto\u2010plasmonic Nanostructures Applied to Surface\u2010Enhanced Raman Spectroscopy"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1297-7057","authenticated-orcid":false,"given":"Tiago","family":"Fernandes","sequence":"first","affiliation":[{"name":"Department of Chemistry CICECO \u2013 Aveiro Institute of Materials University of Aveiro  3810-193 Aveiro Portugal"}]},{"given":"Helena I. 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