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Moreover, the use of implants goes alongside with the threat of pathogens\u2010associated complications. In this study, PEO coated Mg biomaterial loaded with antibacterial Ag(I) and Cu(II) complexes is produced and tested to meet both appropriate protective characteristics as well as sufficient level of antibacterial activity. To achieve a suitable level of anticorrosion protection phosphate and fluoride\u2010phosphate electrolytes are used in the PEO process. Investigation of the surface thickness and morphology done by means of cross\u2010section analysis and scanning electron microscopy (SEM), as well as electrochemical impedance spectroscopy (EIS) assay show precedence of the fluoride containing PEO coating and make it the material of choice for further modification with Ag(I) and Cu(II) complexes. The presence of the complexes on the PEO surface is confirmed by energy dispersive X\u2010ray spectroscopy (EDX). X\u2010ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) and glow discharge optical emission spectroscopy (GDOES) are used to estimate the complexes\u2019 chemical state and depth of penetration in the coating surface. Based on the results of antibacterial assay, the modified coatings are found to be active against both Gram\u2010positive and Gram\u2010negative bacteria.<\/jats:p>","DOI":"10.1002\/chem.202303012","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T15:59:47Z","timestamp":1706111987000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Characterization and In Vitro Behavior of PEO Coated Mg Modified with Antibacterial Ag(I) and Cu(II) Complexes"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1931-3915","authenticated-orcid":false,"given":"Kseniya A.","family":"Tsimafeyeva","sequence":"first","affiliation":[{"name":"Institute of Surface Science Helmholtz-Zentrum hereon GmbH  21502 Geesthacht Germany"}]},{"given":"Maksim","family":"Starykevich","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering and Ceramic University of Aveiro  3810-193 Aveiro Portugal"}]},{"given":"Darya","family":"Snihirova","sequence":"additional","affiliation":[{"name":"Institute of Surface Science Helmholtz-Zentrum hereon GmbH  21502 Geesthacht Germany"}]},{"given":"Carsten","family":"Blawert","sequence":"additional","affiliation":[{"name":"Institute of Surface Science Helmholtz-Zentrum hereon GmbH  21502 Geesthacht Germany"}]},{"given":"Nico","family":"Scharnagl","sequence":"additional","affiliation":[{"name":"Institute of Surface Science Helmholtz-Zentrum hereon GmbH  21502 Geesthacht Germany"}]},{"given":"Anke","family":"Schuster","sequence":"additional","affiliation":[{"name":"Institute of Metallic Biomaterials Helmholtz-Zentrum hereon GmbH  21502 Geesthacht Germany"}]},{"given":"Sarkis","family":"Gavras","sequence":"additional","affiliation":[{"name":"Institute of Metallic Biomaterials Helmholtz-Zentrum hereon GmbH  21502 Geesthacht Germany"}]},{"given":"B\u00e9reng\u00e8re J. 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