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The resulting systems were endowed with relaxometry and photoluminescent properties, respectively. Grafting a pyridine\u2010based aromatic backbone on to the silica surface enhances the emission quantum yield of the Eu<jats:sup>3+<\/jats:sup>\u2010containing nanoparticles fivefold compared to similar systems that bear no aromatic antennae. The emission properties of the mixed Ln<jats:sup>3+<\/jats:sup>\/Gd<jats:sup>3+<\/jats:sup>\u2010based nanoparticles are not influenced by the presence of Gd<jats:sup>3+<\/jats:sup>. The relaxometric properties of these samples are slightly better than the properties of commercial [Gd(DTPA)]<jats:sub>2<\/jats:sub> (DTPA = diethylenetriaminepentaacetate). When taken up by RAW 264.7 cells (mouse macrophage cell line), such bimodal probes exhibit both <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub>\u2010weighted MRI increased contrast and fluorescence tracking.<\/jats:p>","DOI":"10.1002\/ejic.201101110","type":"journal-article","created":{"date-parts":[[2012,1,19]],"date-time":"2012-01-19T05:36:54Z","timestamp":1326951414000},"page":"2828-2837","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Silica Nanoparticles for Bimodal MRI\u2013Optical Imaging by Grafting Gd<sup>3+<\/sup> and Eu<sup>3+<\/sup>\/Tb<sup>3+<\/sup> Complexes"],"prefix":"10.1002","volume":"2012","author":[{"given":"Sonia L. C.","family":"Pinho","sequence":"first","affiliation":[]},{"given":"Henrique","family":"Faneca","sequence":"additional","affiliation":[]},{"given":"Carlos F. G. 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