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Herein we report methodology using azodicarboxylates as efficient reagents for the facile synthesis of cyclic peptides through a disulfide bridge. The utility of this approach in both solution and solid\u2010phase, and compatibility with common amino acid side chain functionalities is demonstrated, resulting in cyclic peptides in good yield and purity. This approach has significant potential application for synthesis of molecules of biological or therapeutic significance.<\/jats:p>","DOI":"10.1002\/ejoc.202300789","type":"journal-article","created":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T08:48:58Z","timestamp":1691743738000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Azodicarboxylate\u2010Mediated Peptide Cyclisation: Application to Disulfide Bond Formation in Solution and Solid Phase"],"prefix":"10.1002","volume":"26","author":[{"given":"Alexandra R. 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