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Electrodes with the best responses were based on plastic membranes containing 31% (w\/w) PVC, 68% (w\/w) of dibutylphthalate as plasticizer and 1% (w\/w) of <jats:italic>\u03b2<\/jats:italic>\u2010cyclodextrin as ionophore. The electrodes were responsive over 6\u2005months to tetracycline, oxytetracycline, doxycycline and chlortetracycline in glycine buffer solution (pH\u20052), in the dynamic range 2\u00d710<jats:sup>\u22125<\/jats:sup>\u201310<jats:sup>\u22122<\/jats:sup> mol L<jats:sup>\u22121<\/jats:sup> with a constant slope of about 55\u2005mV\/dec To enable large scale analysis reducing wastes as associated costs tubular shape electrodes were coupled to a sequential\u2010injection analysis system and its performance evaluated using pharmaceutical samples and waste waters from a treatment facility. The sample throughput of 51 samples h<jats:sup>\u22121<\/jats:sup> was enabled by the system as well as results that favorably agree with those provided by chromatographic analysis.<\/jats:p>","DOI":"10.1002\/elan.201000301","type":"journal-article","created":{"date-parts":[[2010,11,6]],"date-time":"2010-11-06T11:23:37Z","timestamp":1289042617000},"page":"2967-2972","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Tetracycline Potentiometric Sensor Based on Cyclodextrin for Pharmaceuticals and Waste Water Analysis"],"prefix":"10.1002","volume":"22","author":[{"given":"Cl\u00e1udia O.","family":"Cunha","sequence":"first","affiliation":[]},{"given":"Rita C. 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