{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:10:21Z","timestamp":1780107021156,"version":"3.54.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T00:00:00Z","timestamp":1630713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>The long\u2010term evolution of COVID\u201019 is unknown, making it necessary to study the persistence of symptoms over time and their impact on quality of life in people who have had the disease. We analyzed these aspects 1 year after admission for COVID\u201019 and explored the influence of treatment with systemic corticosteroids during the acute phase of the illness. This observational cohort study took place in a tertiary hospital in March and April 2021 and included people admitted due to infection with SARS\u2010CoV\u20102 in March, April, or May 2020. We excluded patients who had died, were unreachable or had substantial cognitive impairment. A telephone survey was undertaken to assess the presence of symptoms related to COVID\u201019 and to administer the SF\u201036 quality of life questionnaire. Other variables collected were demographic and clinical data along with the treatment received and the evolution over time. We analyzed 76 patients, including 44 who did not receive corticosteroids and 32 who did. Most symptoms were less frequent in the group that received corticosteroids, with statistically significant differences for headache, dysphagia, chest pain, and depression. These patients also showed significantly better outcomes in the SF\u201036 domains for \u201cbodily pain\u201d and \u201cmental health.\u201d Corticosteroids administered in the acute phase of COVID\u201019 could attenuate the presence of long\u2010term symptoms and improve patients\u2019 quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.27296","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T12:59:47Z","timestamp":1629982787000},"page":"205-210","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Corticosteroids for COVID\u201019 symptoms and quality of life at 1 year from admission"],"prefix":"10.1002","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2146-378X","authenticated-orcid":false,"given":"Ignacio P\u00e9rez","family":"Catal\u00e1n","sequence":"first","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia Roig","family":"Mart\u00ed","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Palomo de la","family":"Sota","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro Cardenal","family":"\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jos\u00e9 Esteve","family":"Gimeno","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Fabra","family":"Juana","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germ\u00e1n Herrero","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Dom\u00ednguez","family":"Bajo","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria Tornador","family":"Gaya","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Us\u00f3","family":"Blasco","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Castellon Castellon Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Manuel Ramos","family":"Rinc\u00f3n","sequence":"additional","affiliation":[{"name":"Internal Medicine Service University General Hospital of Alicante Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Ministerio de Sanidad.consumo y bienestar social;2021. Accessed April 27 2021.https:\/\/www.mscbs.gob.es\/profesionales\/saludPublica\/ccayes\/alertasActual\/nCov\/situacionActual.html"},{"key":"e_1_2_9_3_1","unstructured":"Johns Hopkins Coronavirus Resource Center. Accessed April 27 2021.https:\/\/coronavirus.jhu.edu\/map.html"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0916-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30628-0"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.12839"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa964"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436"},{"key":"e_1_2_9_9_1","unstructured":"COVID\u201019 rapid guideline: managing the long\u2010term effects of COVID\u201019. London: National Institute for Health and Care Excellence (UK);2020."},{"key":"e_1_2_9_10_1","unstructured":"Brito\u2010Zer\u00f3nP ConanglaL KostovB et al. Manifestaciones persistentes de la COVID\u201019. Gu\u00eda de pr\u00e1ctica cl\u00ednica [Internet]. 1st ed. Barcelona: Sociedad Catalana de Medicina Familiar i Comunit\u00e0ria (CAMFiC) 2020. 1\u201343. 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