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Basic Microbiol."],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:label\/><jats:p>The efficacy of a rhizobacterium <jats:italic>Streptomyces<\/jats:italic> <jats:italic>aurantiogriseus<\/jats:italic> VSMGT1014 for the production of bioactive metabolites with antifungal properties was evaluated under <jats:italic>in vitro<\/jats:italic> conditions. The production of bioactive metabolites by <jats:italic>S. aurantiogriseus<\/jats:italic> VSMGT1014 in International Streptomyces Project\u20102 (ISP\u20102) broth, supplemented with glucose and ammonium acetate was found to be the most suitable carbon and nitrogen sources for the maximum production of bioactive metabolites against rice pathogen, <jats:italic>Rhizoctonia solani<\/jats:italic>. The zone of inhibition range from 23.5 to 28.5\u2009mm and 10.3 to 18.3\u2009mm for glucose and ammonium acetate supplemented media, respectively. The culture filtrate of <jats:italic>S<\/jats:italic>. <jats:italic>aurantiogriseus<\/jats:italic> VSMGT1014 at pH 7.5, 37\u2009\u00b0C at 120\u2009rpm in 6 days of incubation showed the maximum production of bioactive metabolites with antagonistic potential. The crude metabolite was characterized by different spectral studies such as Ultraviolet spectrum, infrared\u2010spectrum and based on the different analytical techniques, including thin layer chromatography (TLC) and high performance liquid chromatography (HPLC) with the retention time 29.4 and the bioactive metabolite was identified as phenazine, which was confirmed by pure phenazine compound as positive control.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jobm.201500362","type":"journal-article","created":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T08:53:54Z","timestamp":1449046434000},"page":"153-161","source":"Crossref","is-referenced-by-count":17,"title":["Enhanced production of phenazine\u2010like metabolite produced by <i>Streptomyces aurantiogriseus<\/i> VSMGT1014 against rice pathogen, <i>Rhizoctonia solani<\/i>"],"prefix":"10.1002","volume":"56","author":[{"given":"Hariharan","family":"Harikrishnan","sequence":"first","affiliation":[{"name":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University Tamil Nadu India"}]},{"given":"Vellasamy","family":"Shanmugaiah","sequence":"additional","affiliation":[{"name":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University Tamil Nadu India"},{"name":"Department of Biology Rutgers University Camden NJ USA"}]},{"given":"Karmegham","family":"Nithya","sequence":"additional","affiliation":[{"name":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University Tamil Nadu India"}]},{"given":"Natesan","family":"Balasubramanian","sequence":"additional","affiliation":[{"name":"UCIBIO and Department of Life Sciences, Faculty of Science and Technology New University of Lisbon Caparica Portugal"}]},{"given":"Mahaveer P.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Microbiology Section ICAR\u2010Directorate of Soybean Research (ICAR\u2010DSR Indore) Indore India"}]},{"given":"Emma W.","family":"Gachomo","sequence":"additional","affiliation":[{"name":"Department of Biology Rutgers University Camden NJ USA"},{"name":"Center for Computational and Integrative Biology Rutgers University Camden NJ USA"}]},{"given":"Simeon O.","family":"Kotchoni","sequence":"additional","affiliation":[{"name":"Department of Biology Rutgers University Camden NJ USA"},{"name":"Center for Computational and Integrative Biology Rutgers University Camden NJ USA"}]}],"member":"311","published-online":{"date-parts":[[2015,12,2]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Kieser T. 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