{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:50:00Z","timestamp":1769043000271,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T00:00:00Z","timestamp":1716595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["CEECIND\/00278\/2018"],"award-info":[{"award-number":["CEECIND\/00278\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["PD\/BDE\/143107\/2018"],"award-info":[{"award-number":["PD\/BDE\/143107\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UID\/FIS\/04559\/2020"],"award-info":[{"award-number":["UID\/FIS\/04559\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Raman Spectroscopy"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This paper addresses the challenge posed by the size of certain objects that do not conform to the constraints of microscope\u2010coupled Raman spectrometers, making sample collection impossible due to their inherent value or nature. Specifically, materials like hydroxyapatite\u2010based substances used in artistic and ornamental carvings, such as bone or ivory, fall within this problematic category. The focus of this study is the enhancement of analytical capabilities in the context of large objects using a Raman microscope system. The study details the innovation involving a remote probe integrated with fiber optics, elaborating on the design and performance aspects, and emphasizing the appropriateness of chosen components in the analysis of ivory artifacts belonging to private collectors. In order to assess the robustness of our discriminative approaches, an archaeological bone and the exposed dentine in a human tooth were also evaluated and compared. Results showed that using an 805\u2010nm longpass dichroic mirror successfully directed the near\u2010infrared laser onto the samples and significantly suppressed the Rayleigh scattering contribution to the spectrum. Regarding the preprocessing methods to spectra evaluation essayed, the most promising approach was the use of principal component analysis for dimension reduction followed by k\u2010means cluster analysis. By leveraging the complementary strengths of PCA and k\u2010means clustering, the robustness and interpretability of clustering analyses are enhanced.<\/jats:p>","DOI":"10.1002\/jrs.6704","type":"journal-article","created":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T10:36:12Z","timestamp":1716633372000},"page":"975-981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Expanding the horizons: Raman probe development and spectra preprocessing evaluation for recognition of large hydroxyapatite\u2010based samples"],"prefix":"10.1002","volume":"55","author":[{"given":"Sofia","family":"Pessanha","sequence":"first","affiliation":[{"name":"NOVA School of Science and Technology, Campus Caparica  Caparica Portugal"},{"name":"Laboratory of Instrumentation, Biomedical Engineering and Radiation Physics (LIBPhys\u2010REAL)  Lisbon Portugal"}]},{"given":"Iulian","family":"Otel","sequence":"additional","affiliation":[{"name":"NOVA School of Science and Technology, Campus Caparica  Caparica Portugal"}]},{"given":"Valentina","family":"Vassilenko","sequence":"additional","affiliation":[{"name":"NOVA School of Science and Technology, Campus Caparica  Caparica Portugal"},{"name":"Laboratory of Instrumentation, Biomedical Engineering and Radiation Physics (LIBPhys\u2010REAL)  Lisbon Portugal"}]},{"given":"Jo\u00e3o M.","family":"Silveira","sequence":"additional","affiliation":[{"name":"Laboratory of Instrumentation, Biomedical Engineering and Radiation Physics (LIBPhys\u2010REAL)  Lisbon Portugal"},{"name":"Faculty of Dentistry University of Lisbon  Lisbon Portugal"}]},{"given":"Paulo","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"NOVA School of Science and Technology, Campus Caparica  Caparica Portugal"},{"name":"Laboratory of Instrumentation, Biomedical Engineering and Radiation Physics (LIBPhys\u2010REAL)  Lisbon Portugal"}]}],"member":"311","published-online":{"date-parts":[[2024,5,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1179\/sic.1998.43.1.9"},{"key":"e_1_2_6_3_1","first-page":"49","volume":"435","author":"Edwards H. G. M.","year":"1997","journal-title":"Spectrosc. Anal. Assign."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1366\/0003702971941674"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003702820930037"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.3010"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.1288"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8JA00370J"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(00)01206-X"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.6487"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(00)01206-X"},{"key":"e_1_2_6_12_1","unstructured":"https:\/\/www.thorlabs.com\/thorproduct.cfm?partnumber=DMLP805R"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5JA00340G"},{"key":"e_1_2_6_14_1","unstructured":"A. R.Ubbelohde In course of publication. Ubbelohde 1938 vol.167."},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2011.06.043"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2018.00257"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-005-0011-z"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.4883"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2020.118378"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-50443-2"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijadhadh.2017.11.005"}],"container-title":["Journal of Raman Spectroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jrs.6704","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T12:43:34Z","timestamp":1760877814000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jrs.6704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,25]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/jrs.6704"],"URL":"https:\/\/doi.org\/10.1002\/jrs.6704","archive":["Portico"],"relation":{},"ISSN":["0377-0486","1097-4555"],"issn-type":[{"value":"0377-0486","type":"print"},{"value":"1097-4555","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,25]]},"assertion":[{"value":"2024-01-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}