{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T18:19:15Z","timestamp":1759515555298},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":4858,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[1993,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied nine cases of oncocytic tumors of salivary gland type in order to evaluate their clinico\u2010pathologic profiles and nuclear DNA patterns as criteria for the differential diagnosis between benign and malignant forms. The tumors were located at the parotid gland, palate, and orbit. The age of the patients ranged between 35 and 85 years and the sex ratio (F:M) was 1:0.8. Seven tumors were capsulated and typical cytology: they were composed of polyhedrical cells with large, eosinophilic, and granular cytoplasm and dark nucleus. The remaining two tumors exhibited malignancy criteria for the oncocytic tumors: atypia, pleomorphism, and mitosis. The evaluation of the nuclear DNA content was also distinct: benign tumors had a DNA diploid pattern and the malignant neoplasms displayed a DNA aneuploid pattern. These observations point to DNA nuclear assessment as an additional criterion to discriminate neoplasms with divergent clinical behavior and prognosis. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jso.2930520404","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T13:02:38Z","timestamp":1171976558000},"page":"217-222","source":"Crossref","is-referenced-by-count":5,"title":["Oncocytic tumors of salivary gland type: A study with emphasis on nuclear DNA ploidy"],"prefix":"10.1002","volume":"52","author":[{"given":"Ana","family":"F\u00e9lix","sequence":"first","affiliation":[]},{"given":"Isabel","family":"Fonseca","sequence":"additional","affiliation":[]},{"given":"Jorge","family":"Soares","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"328","article-title":"Classification of glandular tumors of salivary glands, study of 143 cases","volume":"55","author":"Bauer WH","year":"1953","journal-title":"Arch Pathol"},{"key":"e_1_2_1_3_2","first-page":"567","article-title":"Ultrastructure of oncocytomas of the parotid gland","volume":"23","author":"Tandler B","year":"1970","journal-title":"Lab Invest"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197609)38:3<1306::AID-CNCR2820380333>3.0.CO;2-A"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199106000-00002"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197004)25:4<919::AID-CNCR2820250427>3.0.CO;2-7"},{"issue":"1","key":"e_1_2_1_7_2","first-page":"263","article-title":"Oncocytes, oncocytomas, oncocytic tumors","volume":"27","author":"Chang A","year":"1992","journal-title":"Pathol Ann"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(11)80220-7"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100064811"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711460106"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00430674"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(88)90193-4"},{"key":"e_1_2_1_13_2","first-page":"221","article-title":"Malignant oncocytic adenocarcinoma of the parotid gland with metastases to bone","volume":"3","author":"Haberman RS","year":"1990","journal-title":"Surg Pathol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(86)90004-8"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.37.9.961"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/92.6.711"},{"key":"e_1_2_1_17_2","first-page":"7","article-title":"Acinic cell carcinoma of salivary glands. A long term follow\u2010up study of 15 cases","volume":"18","author":"Oliveira P","year":"1992","journal-title":"Eur J Surg Oncol"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890215)63:4<708::AID-CNCR2820630419>3.0.CO;2-Z"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.2930520404","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.2930520404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T05:10:06Z","timestamp":1698210606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.2930520404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,4]]}},"alternative-id":["10.1002\/jso.2930520404"],"URL":"https:\/\/doi.org\/10.1002\/jso.2930520404","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4]]}}}